Clinical Trials Listing
Here you will find a growing list of clinical trials in the U.S. and beyond hosted by various organizations and companies to test new and exciting treatments for various types of arthritis. The list is organized by geographic location.
Global
"TASKi: Treatment of Arthritis With Syk Kinase Inhibition"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Contact info: http://www.taskistudy.com/Page.aspx?Page=Screen9
The TASKi study is composed of two studies.
(1) A Phase II, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel Dose Study of R935788 in Patients with Rheumatoid Arthritis who have failed at least one biologic.
(2) A Phase II, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel Dose Study of Two Doses of R935788 in Rheumatoid Arthritis Patients Failing to respond to Methotrexate.
Criteria for admittance and further information can be found here:
http://www.taskistudy.com/PreScreen.aspx
Additional information can be found here:
http://www.taskistudy.com
United States - State-by-state
Alabama
"FILM: The Safety and Efficacy of Ocrelizumab in Combination With Methotrexate in Patients With Active Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Auburn, Tuscaloosa
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX), compared with
methotrexate alone in patients with active RA of at least 3 months and
less than 5 years duration (and who are naive to MTX).
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00485589?term=FILM&rank=7
Additional information can be found here:
http://www.researchra.com/
"STAGE: Ocrelizumab Compared to Placebo in Patients With Active Rheumatoid Arthritis Continuing Methotrexate Treatment"
Type(s) of arthritis being studied: Rheumatoid
Status of study: NO LONGER ENROLLING
Study sites can be found in: Anniston, Auburn, Tuscaloosa, Birmingham, Huntsville
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX) in patients with
active RA who have an inadequate response to MTX therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00406419?term=STAGE+AND+RA&rank=15
Additional information can be found here:
http://www.researchra.com/
"SCRIPT: Ocrelizumab Compared to Placebo in
Patients With Active Rheumatoid Arthritis Who Don't Have a Response to
Anti-TNF-A Therapy"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Anniston, Tuscaloosa, Birmingham, Huntsville
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX) or leflunomide,
given either alone or in combination with other non-biologic DMARDs in
patients with active RA who have an inadequate response to anti-TNF-A
therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00476996?term=SCRIPT&rank=3
Additional information can be found here:
http://www.researchra.com/
"PRECISION : Prospective Randomized Evaluation of Celecoxib Integrated Safety vs. Ibuprofen Or Naproxen"
Type(s) of arthritis being studied: Rheumatoid, osteoarthritis
Status of study: RECRUITING
Study sites can be found in: Huntsville, Haleyville, Hoover, Montgomery, Tuscaloosa
Contact info: Pfizer CTgov Call Center, 1-800-718-1021
This study intends to study the risk of using celecoxib (i.e. Celebrex)
versus the use of NSAIDs for the treatment of arthritic pain. The focus
of risk will be on cardiovascular, gastrointestinal, and renal health.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00346216?order=2
"Efficacy, Safety and Tolerability of ACZ885 in Patients With Active Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Anniston
Contact info: Novartis Pharmaceuticals New Jersey, United States, 1-862-778-8300
This Phase II study intends to collect long-term safety and
tolerability data with 300 mg of experimental drug ACZ885 in patients
with active rheumatoid arthritis (RA).
CriteriaCriteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00471198?order=2
"Safety and Effectiveness Study of
RWJ-445380 Cathepsin-S Inhibitor in Patients With Active Rheumatoid
Arthritis Despite Methotrexate Therapy"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Birmingham, Huntsville
The purpose of this Phase II study is to evaluate the safety and
tolerability of 100, 200, and 300 mg/day doses of RWJ-445380 for up to
12 weeks in patients with active Rheumatoid Arthritis despite
methotrexate therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00425321?order=6
"Efficacy, Safety and Tolerability of ACZ885 in Patients With Active Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Birmingham, Anniston
The purpose of this study is to evaluate risk-benefit of three
subcutaneous dose regimens of ACZ885, added on to stable methotrexate
therapy, compared to placebo in patients with active rheumatoid
arthritis.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00424346?order=7
"A Phase 2 Study to Evaluate the Efficacy and Safety of 60mg of MM-093 in Patients With Active Rheumatoid Arthritis"
Type(s) of arthritis being studied: rheumatoid
Status of study: RECRUITING
Study sites can be found in: Montgomery
Contact info: Jayne Belanger; 978-568-8880, jbelanger@clinquestinc.com
The purpose of this study is to determine whether MM-093 is safe and
effective in the treatment of rheumatoid arthritis.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00458146?order=10
"A Safety and Pharmacokinetics Study in Patients With Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Huntsville
Contact info: 1-877-285-4559 or 1-317-615-4559
The purpose of this study is to examine the safety and tolerability of the LY2189102 antibody in rheumatoid arthritis patients.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00380744?order=15
Alaska
Sorry, no trials available.
Arizona
"FILM: The Safety and Efficacy of Ocrelizumab in Combination With Methotrexate in Patients With Active Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Phoenix, Peoria
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX), compared with
methotrexate alone in patients with active RA of at least 3 months and
less than 5 years duration (and who are naive to MTX).
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00485589?term=FILM&rank=7
Additional information can be found here:
http://www.researchra.com/
"STAGE: Ocrelizumab Compared to Placebo in Patients With Active Rheumatoid Arthritis Continuing Methotrexate Treatment"
Type(s) of arthritis being studied: Rheumatoid
Status of study: NO LONGER ENROLLING
Study sites can be found in: Paradise Valley, Phoenix, Tucson, Peoria
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX) in patients with
active RA who have an inadequate response to MTX therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00406419?term=STAGE+AND+RA&rank=15
Additional information can be found here:
http://www.researchra.com/
"SCRIPT: Ocrelizumab Compared to Placebo in
Patients With Active Rheumatoid Arthritis Who Don't Have a Response to
Anti-TNF-A Therapy"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Tuscon, Paradise Valley, Phoenix
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX) or leflunomide,
given either alone or in combination with other non-biologic DMARDs in
patients with active RA who have an inadequate response to anti-TNF-A
therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00476996?term=SCRIPT&rank=3
Additional information can be found here:
http://www.researchra.com/
"PRECISION : Prospective Randomized Evaluation of Celecoxib Integrated Safety vs. Ibuprofen Or Naproxen"
Type(s) of arthritis being studied: Rheumatoid, osteoarthritis
Status of study: RECRUITING
Study sites can be found in: Phoenix, Glendale, Sierra Vista, Tucson, Peoria, Cottonwood, Scottsdale
Contact info: Pfizer CTgov Call Center, 1-800-718-1021
This study intends to study the risk of using celecoxib (i.e. Celebrex)
versus the use of NSAIDs for the treatment of arthritic pain. The focus
of risk will be on cardiovascular, gastrointestinal, and renal health.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00346216?order=2
"Efficacy, Safety and Tolerability of ACZ885 in Patients With Active Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Tucson, Peoria
Contact info: Novartis Pharmaceuticals New Jersey, United States, 1-862-778-8300
This Phase II study intends to collect long-term safety and
tolerability data with 300 mg of experimental drug ACZ885 in patients
with active rheumatoid arthritis (RA).
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00471198?order=2
"Safety and Effectiveness Study of
RWJ-445380 Cathepsin-S Inhibitor in Patients With Active Rheumatoid
Arthritis Despite Methotrexate Therapy"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Tucson, Paradise Valley
The purpose of this Phase II study is to evaluate the safety and
tolerability of 100, 200, and 300 mg/day doses of RWJ-445380 for up to
12 weeks in patients with active Rheumatoid Arthritis despite
methotrexate therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00425321?order=6
"Efficacy, Safety and Tolerability of ACZ885 in Patients With Active Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Tucson, Peoria
The purpose of this study is to evaluate risk-benefit of three
subcutaneous dose regimens of ACZ885, added on to stable methotrexate
therapy, compared to placebo in patients with active rheumatoid
arthritis.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00424346?order=7
"A Phase 2 Study to Evaluate the Efficacy and Safety of 60mg of MM-093 in Patients With Active Rheumatoid Arthritis"
Type(s) of arthritis being studied: rheumatoid
Status of study: RECRUITING
Study sites can be found in: Scottsdale
Contact info: Jayne Belanger; 978-568-8880, jbelanger@clinquestinc.com
The purpose of this study is to determine whether MM-093 is safe and
effective in the treatment of rheumatoid arthritis.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00458146?order=10
Arkansas
"FILM: The Safety and Efficacy of Ocrelizumab in Combination With Methotrexate in Patients With Active Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Jonesboro, Little Rock
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX), compared with
methotrexate alone in patients with active RA of at least 3 months and
less than 5 years duration (and who are naive to MTX).
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00485589?term=FILM&rank=7
Additional information can be found here:
http://www.researchra.com/
"STAGE: Ocrelizumab Compared to Placebo in Patients With Active Rheumatoid Arthritis Continuing Methotrexate Treatment"
Type(s) of arthritis being studied: Rheumatoid
Status of study: NO LONGER ENROLLING
Study sites can be found in: Jonesboro, Hot Springs, Little Rock
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX) in patients with
active RA who have an inadequate response to MTX therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00406419?term=STAGE+AND+RA&rank=15
Additional information can be found here:
http://www.researchra.com/
"SCRIPT: Ocrelizumab Compared to Placebo in
Patients With Active Rheumatoid Arthritis Who Don't Have a Response to
Anti-TNF-A Therapy"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Hot Springs, Little Rock
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX) or leflunomide,
given either alone or in combination with other non-biologic DMARDs in
patients with active RA who have an inadequate response to anti-TNF-A
therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00476996?term=SCRIPT&rank=3
Additional information can be found here:
http://www.researchra.com/
"PRECISION : Prospective Randomized Evaluation of Celecoxib Integrated Safety vs. Ibuprofen Or Naproxen"
Type(s) of arthritis being studied: Rheumatoid, osteoarthritis
Status of study: RECRUITING
Study sites can be found in: Fayetteville
Contact info: Pfizer CTgov Call Center, 1-800-718-1021
This study intends to study the risk of using celecoxib (i.e. Celebrex)
versus the use of NSAIDs for the treatment of arthritic pain. The focus
of risk will be on cardiovascular, gastrointestinal, and renal health.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00346216?order=2
"Long-Term Effectiveness And Safety Of CP-690,550 For The Treatment Of Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Hot Springs
Contact info: Pfizer CTgov Call Center, 1-800-718-1021
The purpose of this study is to determine the long-term effectiveness
and safety of CP-690,550 for the treatment of rheumatoid arthritis.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00413699?order=12
California
"TASKi: Treatment of Arthritis With Syk Kinase Inhibition"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Palm Desert, San Diego, Palo Alto, Palm Springs, and La Jolla
Contact info: http://www.taskistudy.com/Page.aspx?Page=Screen9
The TASKi study is composed of two studies.
(1)
A Phase II, Multicenter, Randomized, Double-Blind, Placebo-Controlled,
Parallel Dose Study of R935788 in Patients with Rheumatoid Arthritis
who have failed at least one biologic.
(2) A Phase II, Multicenter,
Randomized, Double-Blind, Placebo-Controlled, Parallel Dose Study of
Two Doses of R935788 in Rheumatoid Arthritis Patients Failing to
respond to Methotrexate.
Criteria for admittance and further information can be found here:
http://www.taskistudy.com/PreScreen.aspx
Additional information can be found here:
http://www.taskistudy.com
"FILM: The Safety and Efficacy of Ocrelizumab in Combination With Methotrexate in Patients With Active Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Los Angeles, San Diego, Long Beach, Santa Maria, Upland, San Leandro, Pasadena
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX), compared with
methotrexate alone in patients with active RA of at least 3 months and
less than 5 years duration (and who are naive to MTX).
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00485589?term=FILM&rank=7
Additional information can be found here:
http://www.researchra.com/
"STAGE: Ocrelizumab Compared to Placebo in Patients With Active Rheumatoid Arthritis Continuing Methotrexate Treatment"
Type(s) of arthritis being studied: Rheumatoid
Status of study: NO LONGER ENROLLING
Study sites can be found in: Los Angeles, San Diego, Upland, San Leandro, Northridge, Pasadena
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX) in patients with
active RA who have an inadequate response to MTX therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00406419?term=STAGE+AND+RA&rank=15
Additional information can be found here:
http://www.researchra.com/
"SCRIPT: Ocrelizumab Compared to Placebo in
Patients With Active Rheumatoid Arthritis Who Don't Have a Response to
Anti-TNF-A Therapy"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Los Angeles, Long Beach, Palo Alto, San Jose, San Diego, Torrance, La Jolla, San Leandro
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX) or leflunomide,
given either alone or in combination with other non-biologic DMARDs in
patients with active RA who have an inadequate response to anti-TNF-A
therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00476996?term=SCRIPT&rank=3
Additional information can be found here:
http://www.researchra.com/
"PRECISION : Prospective Randomized Evaluation of Celecoxib Integrated Safety vs. Ibuprofen Or Naproxen"
Type(s) of arthritis being studied: Rheumatoid, osteoarthritis
Status of study: RECRUITING
Study sites can be found in: San Diego, Westlake Village, Huntington
Beach, Stockton, Upland, Santa Maria, Santa Rosa, Roseville,
Carmichael, Greenbrae, Laguna Hills, Sacramento, Van Nuys, Huntington
Park, Long Beach, Burbank, Pasadena, San Luis Obispo, Palm Springs
Contact info: Pfizer CTgov Call Center, 1-800-718-1021
This study intends to study the risk of using celecoxib (i.e. Celebrex)
versus the use of NSAIDs for the treatment of arthritic pain. The focus
of risk will be on cardiovascular, gastrointestinal, and renal health.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00346216?order=2
"Multiple Ascending Dose Study of BMS-582949 in Patients With Stable Rheumatoid Arthritis on the Methotrexate Background"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Palm Desert, Upland
This study intends to study the safety of taking methotrexate with BMS-582949.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00162292?order=3
"Safety and Effectiveness Study of
RWJ-445380 Cathepsin-S Inhibitor in Patients With Active Rheumatoid
Arthritis Despite Methotrexate Therapy"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Fair Oaks, Whittier
The purpose of this Phase II study is to evaluate the safety and
tolerability of 100, 200, and 300 mg/day doses of RWJ-445380 for up to
12 weeks in patients with active Rheumatoid Arthritis despite
methotrexate therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00425321?order=6
"Treatment of Arthritis With Syk Kinase Inhibition (TASKI-1)"
Type(s) of arthritis being studied: rheumatoid
Status of study: RECRUITING
Study sites can be found in: Santa Maria
Contact info: Elliott Grossbard, M.D.; 650-624-1378, egrossbard@rigel.com
The goal of this study is to assess the preliminary efficacy of up to three different dosage regimens of R788.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00326339?order=7
"A Phase 2 Study to Evaluate the Efficacy and Safety of 60mg of MM-093 in Patients With Active Rheumatoid Arthritis"
Type(s) of arthritis being studied: rheumatoid
Status of study: RECRUITING
Study sites can be found in: Santa Maria
Contact info: Jayne Belanger; 978-568-8880, jbelanger@clinquestinc.com
The purpose of this study is to determine whether MM-093 is safe and
effective in the treatment of rheumatoid arthritis.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00458146?order=10
"Long-Term Effectiveness And Safety Of CP-690,550 For The Treatment Of Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Upland
Contact info: Pfizer CTgov Call Center, 1-800-718-1021
The purpose of this study is to determine the long-term effectiveness
and safety of CP-690,550 for the treatment of rheumatoid arthritis.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00413699?order=12
"A Safety and Pharmacokinetics Study in Patients With Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Upland
Contact info: 1-877-285-4559 or 1-317-615-4559
The purpose of this study is to examine the safety and tolerability of the LY2189102 antibody in rheumatoid arthritis patients.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00380744?order=15
Colorado
"TASKi: Treatment of Arthritis With Syk Kinase Inhibition"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Colorado Springs
Contact info: http://www.taskistudy.com/Page.aspx?Page=Screen9
The TASKi study is composed of two studies.
(1)
A Phase II, Multicenter, Randomized, Double-Blind, Placebo-Controlled,
Parallel Dose Study of R935788 in Patients with Rheumatoid Arthritis
who have failed at least one biologic.
(2) A Phase II, Multicenter,
Randomized, Double-Blind, Placebo-Controlled, Parallel Dose Study of
Two Doses of R935788 in Rheumatoid Arthritis Patients Failing to
respond to Methotrexate.
Criteria for admittance and further information can be found here:
http://www.taskistudy.com/PreScreen.aspx
Additional information can be found here:
http://www.taskistudy.com
"STAGE: Ocrelizumab Compared to Placebo in Patients With Active Rheumatoid Arthritis Continuing Methotrexate Treatment"
Type(s) of arthritis being studied: Rheumatoid
Status of study: NO LONGER ENROLLING
Study sites can be found in: Colorado Springs
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX) in patients with
active RA who have an inadequate response to MTX therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00406419?term=STAGE+AND+RA&rank=15
Additional information can be found here:
http://www.researchra.com/
"SCRIPT: Ocrelizumab Compared to Placebo in
Patients With Active Rheumatoid Arthritis Who Don't Have a Response to
Anti-TNF-A Therapy"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Denver, Colorado Springs
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX) or leflunomide,
given either alone or in combination with other non-biologic DMARDs in
patients with active RA who have an inadequate response to anti-TNF-A
therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00476996?term=SCRIPT&rank=3
Additional information can be found here:
http://www.researchra.com/
"PRECISION : Prospective Randomized Evaluation of Celecoxib Integrated Safety vs. Ibuprofen Or Naproxen"
Type(s) of arthritis being studied: Rheumatoid, osteoarthritis
Status of study: RECRUITING
Study sites can be found in: Golden, Pueblo, Colorado Springs, Highlands Ranch, Littleton, Aurora
Contact info: Pfizer CTgov Call Center, 1-800-718-1021
This study intends to study the risk of using celecoxib (i.e. Celebrex)
versus the use of NSAIDs for the treatment of arthritic pain. The focus
of risk will be on cardiovascular, gastrointestinal, and renal health.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00346216?order=2
"Safety and Effectiveness Study of
RWJ-445380 Cathepsin-S Inhibitor in Patients With Active Rheumatoid
Arthritis Despite Methotrexate Therapy"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Colorado Springs
The purpose of this Phase II study is to evaluate the safety and
tolerability of 100, 200, and 300 mg/day doses of RWJ-445380 for up to
12 weeks in patients with active Rheumatoid Arthritis despite
methotrexate therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00425321?order=6
"A Phase 2 Study to Evaluate the Efficacy and Safety of 60mg of MM-093 in Patients With Active Rheumatoid Arthritis"
Type(s) of arthritis being studied: rheumatoid
Status of study: RECRUITING
Study sites can be found in: Denver
Contact info: Jayne Belanger; 978-568-8880, jbelanger@clinquestinc.com
The purpose of this study is to determine whether MM-093 is safe and
effective in the treatment of rheumatoid arthritis.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00458146?order=10
"Long-Term Effectiveness And Safety Of CP-690,550 For The Treatment Of Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Denver, Golden
Contact info: Pfizer CTgov Call Center, 1-800-718-1021
The purpose of this study is to determine the long-term effectiveness
and safety of CP-690,550 for the treatment of rheumatoid arthritis.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00413699?order=12
"A Safety and Pharmacokinetics Study in Patients With Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Denver
Contact info: 1-877-285-4559 or 1-317-615-4559
The purpose of this study is to examine the safety and tolerability of the LY2189102 antibody in rheumatoid arthritis patients.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00380744?order=15
Connecticut
"TASKi: Treatment of Arthritis With Syk Kinase Inhibition"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: New Haven
Contact info: http://www.taskistudy.com/Page.aspx?Page=Screen9
The TASKi study is composed of two studies.
(1)
A Phase II, Multicenter, Randomized, Double-Blind, Placebo-Controlled,
Parallel Dose Study of R935788 in Patients with Rheumatoid Arthritis
who have failed at least one biologic.
(2) A Phase II, Multicenter,
Randomized, Double-Blind, Placebo-Controlled, Parallel Dose Study of
Two Doses of R935788 in Rheumatoid Arthritis Patients Failing to
respond to Methotrexate.
Criteria for admittance and further information can be found here:
http://www.taskistudy.com/PreScreen.aspx
Additional information can be found here:
http://www.taskistudy.com
"FILM: The Safety and Efficacy of Ocrelizumab in Combination With Methotrexate in Patients With Active Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Hamden, Trumbull
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX), compared with
methotrexate alone in patients with active RA of at least 3 months and
less than 5 years duration (and who are naive to MTX).
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00485589?term=FILM&rank=7
Additional information can be found here:
http://www.researchra.com/
"SCRIPT: Ocrelizumab Compared to Placebo in
Patients With Active Rheumatoid Arthritis Who Don't Have a Response to
Anti-TNF-A Therapy"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Hamden, Trumbull, Waterbury
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX) or leflunomide,
given either alone or in combination with other non-biologic DMARDs in
patients with active RA who have an inadequate response to anti-TNF-A
therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00476996?term=SCRIPT&rank=3
Additional information can be found here:
http://www.researchra.com/
"PRECISION : Prospective Randomized Evaluation of Celecoxib Integrated Safety vs. Ibuprofen Or Naproxen"
Type(s) of arthritis being studied: Rheumatoid, osteoarthritis
Status of study: RECRUITING
Study sites can be found in: Waterbury, Trumbull, Birdgeport, Bristol, Hamden, Stamford
Contact info: Pfizer CTgov Call Center, 1-800-718-1021
This study intends to study the risk of using celecoxib (i.e. Celebrex)
versus the use of NSAIDs for the treatment of arthritic pain. The focus
of risk will be on cardiovascular, gastrointestinal, and renal health.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00346216?order=2
"Safety and Effectiveness Study of
RWJ-445380 Cathepsin-S Inhibitor in Patients With Active Rheumatoid
Arthritis Despite Methotrexate Therapy"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Waterbury
The purpose of this Phase II study is to evaluate the safety and
tolerability of 100, 200, and 300 mg/day doses of RWJ-445380 for up to
12 weeks in patients with active Rheumatoid Arthritis despite
methotrexate therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00425321?order=6
"A Phase 2 Study to Evaluate the Efficacy and Safety of 60mg of MM-093 in Patients With Active Rheumatoid Arthritis"
Type(s) of arthritis being studied: rheumatoid
Status of study: RECRUITING
Study sites can be found in: Bridgeport
Contact info: Jayne Belanger; 978-568-8880, jbelanger@clinquestinc.com
The purpose of this study is to determine whether MM-093 is safe and
effective in the treatment of rheumatoid arthritis.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00458146?order=10
Delaware
"FILM: The Safety and Efficacy of Ocrelizumab in Combination With Methotrexate in Patients With Active Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Newark
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX), compared with
methotrexate alone in patients with active RA of at least 3 months and
less than 5 years duration (and who are naive to MTX).
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00485589?term=FILM&rank=7
Additional information can be found here:
http://www.researchra.com/
"STAGE: Ocrelizumab Compared to Placebo in Patients With Active Rheumatoid Arthritis Continuing Methotrexate Treatment"
Type(s) of arthritis being studied: Rheumatoid
Status of study: NO LONGER ENROLLING
Study sites can be found in: Newark
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX) in patients with
active RA who have an inadequate response to MTX therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00406419?term=STAGE+AND+RA&rank=15
Additional information can be found here:
http://www.researchra.com/
"SCRIPT: Ocrelizumab Compared to Placebo in
Patients With Active Rheumatoid Arthritis Who Don't Have a Response to
Anti-TNF-A Therapy"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Newark, Lewes
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX) or leflunomide,
given either alone or in combination with other non-biologic DMARDs in
patients with active RA who have an inadequate response to anti-TNF-A
therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00476996?term=SCRIPT&rank=3
Additional information can be found here:
http://www.researchra.com/
"PRECISION : Prospective Randomized Evaluation of Celecoxib Integrated Safety vs. Ibuprofen Or Naproxen"
Type(s) of arthritis being studied: Rheumatoid, osteoarthritis
Status of study: RECRUITING
Study sites can be found in: Lewes
Contact info: Pfizer CTgov Call Center, 1-800-718-1021
This study intends to study the risk of using celecoxib (i.e. Celebrex)
versus the use of NSAIDs for the treatment of arthritic pain. The focus
of risk will be on cardiovascular, gastrointestinal, and renal health.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00346216?order=2
"Long-Term Effectiveness And Safety Of CP-690,550 For The Treatment Of Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Newark
Contact info: Pfizer CTgov Call Center, 1-800-718-1021
The purpose of this study is to determine the long-term effectiveness
and safety of CP-690,550 for the treatment of rheumatoid arthritis.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00413699?order=12
District of Columbia
"TASKi: Treatment of Arthritis With Syk Kinase Inhibition"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Contact info: http://www.taskistudy.com/Page.aspx?Page=Screen9
The TASKi study is composed of two studies.
(1)
A Phase II, Multicenter, Randomized, Double-Blind, Placebo-Controlled,
Parallel Dose Study of R935788 in Patients with Rheumatoid Arthritis
who have failed at least one biologic.
(2) A Phase II, Multicenter,
Randomized, Double-Blind, Placebo-Controlled, Parallel Dose Study of
Two Doses of R935788 in Rheumatoid Arthritis Patients Failing to
respond to Methotrexate.
Criteria for admittance and further information can be found here:
http://www.taskistudy.com/PreScreen.aspx
Additional information can be found here:
http://www.taskistudy.com
"STAGE: Ocrelizumab Compared to Placebo in Patients With Active Rheumatoid Arthritis Continuing Methotrexate Treatment"
Type(s) of arthritis being studied: Rheumatoid
Status of study: NO LONGER ENROLLING
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX) in patients with
active RA who have an inadequate response to MTX therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00406419?term=STAGE+AND+RA&rank=15
Additional information can be found here:
http://www.researchra.com/
"PRECISION : Prospective Randomized Evaluation of Celecoxib Integrated Safety vs. Ibuprofen Or Naproxen"
Type(s) of arthritis being studied: Rheumatoid, osteoarthritis
Status of study: RECRUITING
Contact info: Pfizer CTgov Call Center, 1-800-718-1021
This study intends to study the risk of using celecoxib (i.e. Celebrex)
versus the use of NSAIDs for the treatment of arthritic pain. The focus
of risk will be on cardiovascular, gastrointestinal, and renal health.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00346216?order=2
Florida
"TASKi: Treatment of Arthritis With Syk Kinase Inhibition"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Sarasota, Ocala, Gainesville, Orlando, and North Miami
Contact info: http://www.taskistudy.com/Page.aspx?Page=Screen9
The TASKi study is composed of two studies.
(1)
A Phase II, Multicenter, Randomized, Double-Blind, Placebo-Controlled,
Parallel Dose Study of R935788 in Patients with Rheumatoid Arthritis
who have failed at least one biologic.
(2) A Phase II, Multicenter,
Randomized, Double-Blind, Placebo-Controlled, Parallel Dose Study of
Two Doses of R935788 in Rheumatoid Arthritis Patients Failing to
respond to Methotrexate.
Criteria for admittance and further information can be found here:
http://www.taskistudy.com/PreScreen.aspx
Additional information can be found here:
http://www.taskistudy.com
"FILM: The Safety and Efficacy of Ocrelizumab in Combination With Methotrexate in Patients With Active Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Sarasota, Jacksonville, Tampa, Zephyrhills
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX), compared with
methotrexate alone in patients with active RA of at least 3 months and
less than 5 years duration (and who are naive to MTX).
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00485589?term=FILM&rank=7
Additional information can be found here:
http://www.researchra.com/
"STAGE: Ocrelizumab Compared to Placebo in Patients With Active Rheumatoid Arthritis Continuing Methotrexate Treatment"
Type(s) of arthritis being studied: Rheumatoid
Status of study: NO LONGER ENROLLING
Study sites can be found in: Jacksonville, Palm Harbor, Aventura,
Sarasota, Tampa, Orlando, Zephyrhills, St. Petersburg, South Miami
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX) in patients with
active RA who have an inadequate response to MTX therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00406419?term=STAGE+AND+RA&rank=15
Additional information can be found here:
http://www.researchra.com/
"SCRIPT: Ocrelizumab Compared to Placebo in
Patients With Active Rheumatoid Arthritis Who Don't Have a Response to
Anti-TNF-A Therapy"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Orlando, Tampa, Aventura, Sarasota, Palm Harbor, Jacksonville, Zephyrhills, South Miami
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX) or leflunomide,
given either alone or in combination with other non-biologic DMARDs in
patients with active RA who have an inadequate response to anti-TNF-A
therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00476996?term=SCRIPT&rank=3
Additional information can be found here:
http://www.researchra.com/
"PRECISION : Prospective Randomized Evaluation of Celecoxib Integrated Safety vs. Ibuprofen Or Naproxen"
Type(s) of arthritis being studied: Rheumatoid, osteoarthritis
Status of study: RECRUITING
Study sites can be found in: Destin, Miami, Ocala, Gainesville, Tampa,
Longwood, Jacksonville, Marianna, Dunedin, Naples, Niceville, Hudson,
Chipley, Sarasota, Daytona Beach, Lake Mary, Largo, Merritt Island,
Ocoee, Clearwater, Atlantis, Palm Harbor, Aventura, Winter Park,
Marathon, Fort Myers, Crystal River, vero Beach, Madeira, Fort
Lauderdale
Contact info: Pfizer CTgov Call Center, 1-800-718-1021
This study intends to study the risk of using celecoxib (i.e. Celebrex)
versus the use of NSAIDs for the treatment of arthritic pain. The focus
of risk will be on cardiovascular, gastrointestinal, and renal health.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00346216?order=2
"Efficacy, Safety and Tolerability of ACZ885 in Patients With Active Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Palm Harbor
Contact info: Novartis Pharmaceuticals New Jersey, United States, 1-862-778-8300
This Phase II study intends to collect long-term safety and
tolerability data with 300 mg of experimental drug ACZ885 in patients
with active rheumatoid arthritis (RA).
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00471198?order=2
"Multiple Ascending Dose Study of BMS-582949 in Patients With Stable Rheumatoid Arthritis on the Methotrexate Background"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Ocala, Delray Beach
This study intends to study the safety of taking methotrexate with BMS-582949.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00162292?order=3
"Safety and Effectiveness Study of
RWJ-445380 Cathepsin-S Inhibitor in Patients With Active Rheumatoid
Arthritis Despite Methotrexate Therapy"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Sarasota
The purpose of this Phase II study is to evaluate the safety and
tolerability of 100, 200, and 300 mg/day doses of RWJ-445380 for up to
12 weeks in patients with active Rheumatoid Arthritis despite
methotrexate therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00425321?order=6
"Efficacy, Safety and Tolerability of ACZ885 in Patients With Active Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Palm Harbor,
The purpose of this study is to evaluate risk-benefit of three
subcutaneous dose regimens of ACZ885, added on to stable methotrexate
therapy, compared to placebo in patients with active rheumatoid
arthritis.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00424346?order=7
"Treatment of Arthritis With Syk Kinase Inhibition (TASKI-1)"
Type(s) of arthritis being studied: rheumatoid
Status of study: RECRUITING
Study sites can be found in: Orange Park, Orlando, South Miami, Ocala, Palm Harbor, Sarasota
Contact info: Elliott Grossbard, M.D.; 650-624-1378, egrossbard@rigel.com
The goal of this study is to assess the preliminary efficacy of up to three different dosage regimens of R788.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00326339?order=7
"A Phase 2 Study to Evaluate the Efficacy and Safety of 60mg of MM-093 in Patients With Active Rheumatoid Arthritis"
Type(s) of arthritis being studied: rheumatoid
Status of study: RECRUITING
Study sites can be found in: Aventura
Contact info: Jayne Belanger; 978-568-8880, jbelanger@clinquestinc.com
The purpose of this study is to determine whether MM-093 is safe and
effective in the treatment of rheumatoid arthritis.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00458146?order=10
"Long-Term Effectiveness And Safety Of CP-690,550 For The Treatment Of Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Orlando, Ocala, Tampa
Contact info: Pfizer CTgov Call Center, 1-800-718-1021
The purpose of this study is to determine the long-term effectiveness
and safety of CP-690,550 for the treatment of rheumatoid arthritis.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00413699?order=12
"A Safety and Pharmacokinetics Study in Patients With Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Vero Beach, Port Orange, Tampa, Miami
Contact info: 1-877-285-4559 or 1-317-615-4559
The purpose of this study is to examine the safety and tolerability of the LY2189102 antibody in rheumatoid arthritis patients.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00380744?order=15
Georgia
"STAGE: Ocrelizumab Compared to Placebo in Patients With Active Rheumatoid Arthritis Continuing Methotrexate Treatment"
Type(s) of arthritis being studied: Rheumatoid
Status of study: NO LONGER ENROLLING
Study sites can be found in: Atlanta, Decatur, Rome
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX) in patients with
active RA who have an inadequate response to MTX therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00406419?term=STAGE+AND+RA&rank=15
Additional information can be found here:
http://www.researchra.com/
"SCRIPT: Ocrelizumab Compared to Placebo in
Patients With Active Rheumatoid Arthritis Who Don't Have a Response to
Anti-TNF-A Therapy"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Marietta, Atlanta, Decatur
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX) or leflunomide,
given either alone or in combination with other non-biologic DMARDs in
patients with active RA who have an inadequate response to anti-TNF-A
therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00476996?term=SCRIPT&rank=3
Additional information can be found here:
http://www.researchra.com/
"PRECISION : Prospective Randomized Evaluation of Celecoxib Integrated Safety vs. Ibuprofen Or Naproxen"
Type(s) of arthritis being studied: Rheumatoid, osteoarthritis
Status of study: RECRUITING
Study sites can be found in: Atlanta, Tifton, Suwanee, Valdosta, Rome, Gainsville, Tucker
Contact info: Pfizer CTgov Call Center, 1-800-718-1021
This study intends to study the risk of using celecoxib (i.e. Celebrex)
versus the use of NSAIDs for the treatment of arthritic pain. The focus
of risk will be on cardiovascular, gastrointestinal, and renal health.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00346216?order=2
Hawaii
"PRECISION : Prospective Randomized Evaluation of Celecoxib Integrated Safety vs. Ibuprofen Or Naproxen"
Type(s) of arthritis being studied: Rheumatoid, osteoarthritis
Status of study: RECRUITING
Study sites can be found in: Honolulu
Contact info: Pfizer CTgov Call Center, 1-800-718-1021
This study intends to study the risk of using celecoxib (i.e. Celebrex)
versus the use of NSAIDs for the treatment of arthritic pain. The focus
of risk will be on cardiovascular, gastrointestinal, and renal health.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00346216?order=2
Idaho
"TASKi: Treatment of Arthritis With Syk Kinase Inhibition"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Boise
Contact info: http://www.taskistudy.com/Page.aspx?Page=Screen9
The TASKi study is composed of two studies.
(1)
A Phase II, Multicenter, Randomized, Double-Blind, Placebo-Controlled,
Parallel Dose Study of R935788 in Patients with Rheumatoid Arthritis
who have failed at least one biologic.
(2) A Phase II, Multicenter,
Randomized, Double-Blind, Placebo-Controlled, Parallel Dose Study of
Two Doses of R935788 in Rheumatoid Arthritis Patients Failing to
respond to Methotrexate.
Criteria for admittance and further information can be found here:
http://www.taskistudy.com/PreScreen.aspx
Additional information can be found here:
http://www.taskistudy.com
"FILM: The Safety and Efficacy of Ocrelizumab in Combination With Methotrexate in Patients With Active Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Idaho Falls
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX), compared with
methotrexate alone in patients with active RA of at least 3 months and
less than 5 years duration (and who are naive to MTX).
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00485589?term=FILM&rank=7
Additional information can be found here:
http://www.researchra.com/
"STAGE: Ocrelizumab Compared to Placebo in Patients With Active Rheumatoid Arthritis Continuing Methotrexate Treatment"
Type(s) of arthritis being studied: Rheumatoid
Status of study: NO LONGER ENROLLING
Study sites can be found in: Meridian, Idaho Falls, Coeur d'Alene
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX) in patients with
active RA who have an inadequate response to MTX therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00406419?term=STAGE+AND+RA&rank=15
Additional information can be found here:
http://www.researchra.com/
"SCRIPT: Ocrelizumab Compared to Placebo in
Patients With Active Rheumatoid Arthritis Who Don't Have a Response to
Anti-TNF-A Therapy"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Meridian, Boise, Coeur d'Alene
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX) or leflunomide,
given either alone or in combination with other non-biologic DMARDs in
patients with active RA who have an inadequate response to anti-TNF-A
therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00476996?term=SCRIPT&rank=3
Additional information can be found here:
http://www.researchra.com/
"PRECISION : Prospective Randomized Evaluation of Celecoxib Integrated Safety vs. Ibuprofen Or Naproxen"
Type(s) of arthritis being studied: Rheumatoid, osteoarthritis
Status of study: RECRUITING
Study sites can be found in: Boise, Meridian, Coeur DÕAlene
Contact info: Pfizer CTgov Call Center, 1-800-718-1021
This study intends to study the risk of using celecoxib (i.e. Celebrex)
versus the use of NSAIDs for the treatment of arthritic pain. The focus
of risk will be on cardiovascular, gastrointestinal, and renal health.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00346216?order=2
"Treatment of Arthritis With Syk Kinase Inhibition (TASKI-1)"
Type(s) of arthritis being studied: rheumatoid
Status of study: RECRUITING
Study sites can be found in: Coeur dÕAlene
Contact info: Elliott Grossbard, M.D.; 650-624-1378, egrossbard@rigel.com
The goal of this study is to assess the preliminary efficacy of up to three different dosage regimens of R788.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00326339?order=7
"A Safety and Pharmacokinetics Study in Patients With Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Meridian
Contact info: 1-877-285-4559 or 1-317-615-4559
The purpose of this study is to examine the safety and tolerability of the LY2189102 antibody in rheumatoid arthritis patients.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00380744?order=15
Illinois
"TASKi: Treatment of Arthritis With Syk Kinase Inhibition"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Rockford and Chicago
Contact info: http://www.taskistudy.com/Page.aspx?Page=Screen9
The TASKi study is composed of two studies.
(1)
A Phase II, Multicenter, Randomized, Double-Blind, Placebo-Controlled,
Parallel Dose Study of R935788 in Patients with Rheumatoid Arthritis
who have failed at least one biologic.
(2) A Phase II, Multicenter,
Randomized, Double-Blind, Placebo-Controlled, Parallel Dose Study of
Two Doses of R935788 in Rheumatoid Arthritis Patients Failing to
respond to Methotrexate.
Criteria for admittance and further information can be found here:
http://www.taskistudy.com/PreScreen.aspx
Additional information can be found here:
http://www.taskistudy.com
"FILM: The Safety and Efficacy of Ocrelizumab in Combination With Methotrexate in Patients With Active Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Moline, Springfield
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX), compared with
methotrexate alone in patients with active RA of at least 3 months and
less than 5 years duration (and who are naive to MTX).
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00485589?term=FILM&rank=7
Additional information can be found here:
http://www.researchra.com/
"STAGE: Ocrelizumab Compared to Placebo in Patients With Active Rheumatoid Arthritis Continuing Methotrexate Treatment"
Type(s) of arthritis being studied: Rheumatoid
Status of study: NO LONGER ENROLLING
Study sites can be found in: Morton Grove, Chicago, Moline, Springfield
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX) in patients with
active RA who have an inadequate response to MTX therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00406419?term=STAGE+AND+RA&rank=15
Additional information can be found here:
http://www.researchra.com/
"SCRIPT: Ocrelizumab Compared to Placebo in
Patients With Active Rheumatoid Arthritis Who Don't Have a Response to
Anti-TNF-A Therapy"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Morton Grove, Moline, Chicago, Springfield
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX) or leflunomide,
given either alone or in combination with other non-biologic DMARDs in
patients with active RA who have an inadequate response to anti-TNF-A
therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00476996?term=SCRIPT&rank=3
Additional information can be found here:
http://www.researchra.com/
"PRECISION : Prospective Randomized Evaluation of Celecoxib Integrated Safety vs. Ibuprofen Or Naproxen"
Type(s) of arthritis being studied: Rheumatoid, osteoarthritis
Status of study: RECRUITING
Study sites can be found in: Springfield, Lake Zurich
Contact info: Pfizer CTgov Call Center, 1-800-718-1021
This study intends to study the risk of using celecoxib (i.e. Celebrex)
versus the use of NSAIDs for the treatment of arthritic pain. The focus
of risk will be on cardiovascular, gastrointestinal, and renal health.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00346216?order=2
"Efficacy, Safety and Tolerability of ACZ885 in Patients With Active Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Springfield
Contact info: Novartis Pharmaceuticals New Jersey, United States, 1-862-778-8300
This Phase II study intends to collect long-term safety and
tolerability data with 300 mg of experimental drug ACZ885 in patients
with active rheumatoid arthritis (RA).
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00471198?order=2
"Safety and Effectiveness Study of
RWJ-445380 Cathepsin-S Inhibitor in Patients With Active Rheumatoid
Arthritis Despite Methotrexate Therapy"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Morton Grove, Springfield
The purpose of this Phase II study is to evaluate the safety and
tolerability of 100, 200, and 300 mg/day doses of RWJ-445380 for up to
12 weeks in patients with active Rheumatoid Arthritis despite
methotrexate therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00425321?order=6
"Efficacy, Safety and Tolerability of ACZ885 in Patients With Active Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Springfield
The purpose of this study is to evaluate risk-benefit of three
subcutaneous dose regimens of ACZ885, added on to stable methotrexate
therapy, compared to placebo in patients with active rheumatoid
arthritis.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00424346?order=7
"Treatment of Arthritis With Syk Kinase Inhibition (TASKI-1)"
Type(s) of arthritis being studied: rheumatoid
Status of study: RECRUITING
Study sites can be found in: Springfield
Contact info: Elliott Grossbard, M.D.; 650-624-1378, egrossbard@rigel.com
The goal of this study is to assess the preliminary efficacy of up to three different dosage regimens of R788.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00326339?order=7
"Long-Term Effectiveness And Safety Of CP-690,550 For The Treatment Of Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Rockford
Contact info: Pfizer CTgov Call Center, 1-800-718-1021
The purpose of this study is to determine the long-term effectiveness
and safety of CP-690,550 for the treatment of rheumatoid arthritis.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00413699?order=12
Indiana
"TASKi: Treatment of Arthritis With Syk Kinase Inhibition"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: South Bend
Contact info: http://www.taskistudy.com/Page.aspx?Page=Screen9
The TASKi study is composed of two studies.
(1)
A Phase II, Multicenter, Randomized, Double-Blind, Placebo-Controlled,
Parallel Dose Study of R935788 in Patients with Rheumatoid Arthritis
who have failed at least one biologic.
(2) A Phase II, Multicenter,
Randomized, Double-Blind, Placebo-Controlled, Parallel Dose Study of
Two Doses of R935788 in Rheumatoid Arthritis Patients Failing to
respond to Methotrexate.
Criteria for admittance and further information can be found here:
http://www.taskistudy.com/PreScreen.aspx
Additional information can be found here:
http://www.taskistudy.com
"FILM: The Safety and Efficacy of Ocrelizumab in Combination With Methotrexate in Patients With Active Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Indianapolis
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX), compared with
methotrexate alone in patients with active RA of at least 3 months and
less than 5 years duration (and who are naive to MTX).
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00485589?term=FILM&rank=7
Additional information can be found here:
http://www.researchra.com/
"STAGE: Ocrelizumab Compared to Placebo in Patients With Active Rheumatoid Arthritis Continuing Methotrexate Treatment"
Type(s) of arthritis being studied: Rheumatoid
Status of study: NO LONGER ENROLLING
Study sites can be found in: Munster, Indianapolis
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX) in patients with
active RA who have an inadequate response to MTX therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00406419?term=STAGE+AND+RA&rank=15
Additional information can be found here:
http://www.researchra.com/
"SCRIPT: Ocrelizumab Compared to Placebo in
Patients With Active Rheumatoid Arthritis Who Don't Have a Response to
Anti-TNF-A Therapy"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Munster, Indianapolis
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX) or leflunomide,
given either alone or in combination with other non-biologic DMARDs in
patients with active RA who have an inadequate response to anti-TNF-A
therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00476996?term=SCRIPT&rank=3
Additional information can be found here:
http://www.researchra.com/
"PRECISION : Prospective Randomized Evaluation of Celecoxib Integrated Safety vs. Ibuprofen Or Naproxen"
Type(s) of arthritis being studied: Rheumatoid, osteoarthritis
Status of study: RECRUITING
Study sites can be found in: Merrillville, Avon, Evansville, Jeffersonville, Munster, Indianapolis
Contact info: Pfizer CTgov Call Center, 1-800-718-1021
This study intends to study the risk of using celecoxib (i.e. Celebrex)
versus the use of NSAIDs for the treatment of arthritic pain. The focus
of risk will be on cardiovascular, gastrointestinal, and renal health.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00346216?order=2
"Treatment of Arthritis With Syk Kinase Inhibition (TASKI-1)"
Type(s) of arthritis being studied: rheumatoid
Status of study: RECRUITING
Study sites can be found in: South Bend
Contact info: Elliott Grossbard, M.D.; 650-624-1378, egrossbard@rigel.com
The goal of this study is to assess the preliminary efficacy of up to three different dosage regimens of R788.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00326339?order=7
Iowa
"FILM: The Safety and Efficacy of Ocrelizumab in Combination With Methotrexate in Patients With Active Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Cedar Rapids
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX), compared with
methotrexate alone in patients with active RA of at least 3 months and
less than 5 years duration (and who are naive to MTX).
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00485589?term=FILM&rank=7
Additional information can be found here:
http://www.researchra.com/
"SCRIPT: Ocrelizumab Compared to Placebo in
Patients With Active Rheumatoid Arthritis Who Don't Have a Response to
Anti-TNF-A Therapy"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Cedar Rapids
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX) or leflunomide,
given either alone or in combination with other non-biologic DMARDs in
patients with active RA who have an inadequate response to anti-TNF-A
therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00476996?term=SCRIPT&rank=3
Additional information can be found here:
http://www.researchra.com/
"PRECISION : Prospective Randomized Evaluation of Celecoxib Integrated Safety vs. Ibuprofen Or Naproxen"
Type(s) of arthritis being studied: Rheumatoid, osteoarthritis
Status of study: RECRUITING
Study sites can be found in: Davenport, Waterloo, Cedar Rapids
Contact info: Pfizer CTgov Call Center, 1-800-718-1021
This study intends to study the risk of using celecoxib (i.e. Celebrex)
versus the use of NSAIDs for the treatment of arthritic pain. The focus
of risk will be on cardiovascular, gastrointestinal, and renal health.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00346216?order=2
"Long-Term Effectiveness And Safety Of CP-690,550 For The Treatment Of Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Dubuque
Contact info: Pfizer CTgov Call Center, 1-800-718-1021
The purpose of this study is to determine the long-term effectiveness
and safety of CP-690,550 for the treatment of rheumatoid arthritis.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00413699?order=12
Kansas
"SCRIPT: Ocrelizumab Compared to Placebo in
Patients With Active Rheumatoid Arthritis Who Don't Have a Response to
Anti-TNF-A Therapy"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Kansas City
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX) or leflunomide,
given either alone or in combination with other non-biologic DMARDs in
patients with active RA who have an inadequate response to anti-TNF-A
therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00476996?term=SCRIPT&rank=3
Additional information can be found here:
http://www.researchra.com/
"PRECISION : Prospective Randomized Evaluation of Celecoxib Integrated Safety vs. Ibuprofen Or Naproxen"
Type(s) of arthritis being studied: Rheumatoid, osteoarthritis
Status of study: RECRUITING
Study sites can be found in: Overland Park, Arkansas City
Contact info: Pfizer CTgov Call Center, 1-800-718-1021
This study intends to study the risk of using celecoxib (i.e. Celebrex)
versus the use of NSAIDs for the treatment of arthritic pain. The focus
of risk will be on cardiovascular, gastrointestinal, and renal health.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00346216?order=2
"A Phase 2 Study to Evaluate the Efficacy and Safety of 60mg of MM-093 in Patients With Active Rheumatoid Arthritis"
Type(s) of arthritis being studied: rheumatoid
Status of study: RECRUITING
Study sites can be found in: Wichita
Contact info: Jayne Belanger; 978-568-8880, jbelanger@clinquestinc.com
The purpose of this study is to determine whether MM-093 is safe and
effective in the treatment of rheumatoid arthritis.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00458146?order=10
Kentucky
"TASKi: Treatment of Arthritis With Syk Kinase Inhibition"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Elizabethtown
Contact info: http://www.taskistudy.com/Page.aspx?Page=Screen9
The TASKi study is composed of two studies.
(1)
A Phase II, Multicenter, Randomized, Double-Blind, Placebo-Controlled,
Parallel Dose Study of R935788 in Patients with Rheumatoid Arthritis
who have failed at least one biologic.
(2) A Phase II, Multicenter,
Randomized, Double-Blind, Placebo-Controlled, Parallel Dose Study of
Two Doses of R935788 in Rheumatoid Arthritis Patients Failing to
respond to Methotrexate.
Criteria for admittance and further information can be found here:
http://www.taskistudy.com/PreScreen.aspx
Additional information can be found here:
http://www.taskistudy.com
"FILM: The Safety and Efficacy of Ocrelizumab in Combination With Methotrexate in Patients With Active Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Louisville
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX), compared with
methotrexate alone in patients with active RA of at least 3 months and
less than 5 years duration (and who are naive to MTX).
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00485589?term=FILM&rank=7
Additional information can be found here:
http://www.researchra.com/
"STAGE: Ocrelizumab Compared to Placebo in Patients With Active Rheumatoid Arthritis Continuing Methotrexate Treatment"
Type(s) of arthritis being studied: Rheumatoid
Status of study: NO LONGER ENROLLING
Study sites can be found in: Elizabethtown, Lexington, Louisville
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX) in patients with
active RA who have an inadequate response to MTX therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00406419?term=STAGE+AND+RA&rank=15
Additional information can be found here:
http://www.researchra.com/
"SCRIPT: Ocrelizumab Compared to Placebo in
Patients With Active Rheumatoid Arthritis Who Don't Have a Response to
Anti-TNF-A Therapy"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Elizabethtown, Lexington, Louisville
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX) or leflunomide,
given either alone or in combination with other non-biologic DMARDs in
patients with active RA who have an inadequate response to anti-TNF-A
therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00476996?term=SCRIPT&rank=3
Additional information can be found here:
http://www.researchra.com/
"PRECISION : Prospective Randomized Evaluation of Celecoxib Integrated Safety vs. Ibuprofen Or Naproxen"
Type(s) of arthritis being studied: Rheumatoid, osteoarthritis
Status of study: RECRUITING
Study sites can be found in: Bowling Green, Richmond, Campbellsville, Louisville, Ashland, Lexington
Contact info: Pfizer CTgov Call Center, 1-800-718-1021
This study intends to study the risk of using celecoxib (i.e. Celebrex)
versus the use of NSAIDs for the treatment of arthritic pain. The focus
of risk will be on cardiovascular, gastrointestinal, and renal health.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00346216?order=2
Louisiana
"FILM: The Safety and Efficacy of Ocrelizumab in Combination With Methotrexate in Patients With Active Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Sheveport
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX), compared with
methotrexate alone in patients with active RA of at least 3 months and
less than 5 years duration (and who are naive to MTX).
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00485589?term=FILM&rank=7
Additional information can be found here:
http://www.researchra.com/
"STAGE: Ocrelizumab Compared to Placebo in Patients With Active Rheumatoid Arthritis Continuing Methotrexate Treatment"
Type(s) of arthritis being studied: Rheumatoid
Status of study: NO LONGER ENROLLING
Study sites can be found in: Shreveport
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX) in patients with
active RA who have an inadequate response to MTX therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00406419?term=STAGE+AND+RA&rank=15
Additional information can be found here:
http://www.researchra.com/
"PRECISION : Prospective Randomized Evaluation of Celecoxib Integrated Safety vs. Ibuprofen Or Naproxen"
Type(s) of arthritis being studied: Rheumatoid, osteoarthritis
Status of study: RECRUITING
Study sites can be found in: Bossier City, Shreveport
Contact info: Pfizer CTgov Call Center, 1-800-718-1021
This study intends to study the risk of using celecoxib (i.e. Celebrex)
versus the use of NSAIDs for the treatment of arthritic pain. The focus
of risk will be on cardiovascular, gastrointestinal, and renal health.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00346216?order=2
Maine
"PRECISION : Prospective Randomized Evaluation of Celecoxib Integrated Safety vs. Ibuprofen Or Naproxen"
Type(s) of arthritis being studied: Rheumatoid, osteoarthritis
Status of study: RECRUITING
Study sites can be found in: Auburn
Contact info: Pfizer CTgov Call Center, 1-800-718-1021
This study intends to study the risk of using celecoxib (i.e. Celebrex)
versus the use of NSAIDs for the treatment of arthritic pain. The focus
of risk will be on cardiovascular, gastrointestinal, and renal health.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00346216?order=2
Maryland
"TASKi: Treatment of Arthritis With Syk Kinase Inhibition"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Hagerston
Contact info: http://www.taskistudy.com/Page.aspx?Page=Screen9
The TASKi study is composed of two studies.
(1)
A Phase II, Multicenter, Randomized, Double-Blind, Placebo-Controlled,
Parallel Dose Study of R935788 in Patients with Rheumatoid Arthritis
who have failed at least one biologic.
(2) A Phase II, Multicenter,
Randomized, Double-Blind, Placebo-Controlled, Parallel Dose Study of
Two Doses of R935788 in Rheumatoid Arthritis Patients Failing to
respond to Methotrexate.
Criteria for admittance and further information can be found here:
http://www.taskistudy.com/PreScreen.aspx
Additional information can be found here:
http://www.taskistudy.com
"FILM: The Safety and Efficacy of Ocrelizumab in Combination With Methotrexate in Patients With Active Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Cumberland, Wheaton
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX), compared with
methotrexate alone in patients with active RA of at least 3 months and
less than 5 years duration (and who are naive to MTX).
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00485589?term=FILM&rank=7
Additional information can be found here:
http://www.researchra.com/
"STAGE: Ocrelizumab Compared to Placebo in Patients With Active Rheumatoid Arthritis Continuing Methotrexate Treatment"
Type(s) of arthritis being studied: Rheumatoid
Status of study: NO LONGER ENROLLING
Study sites can be found in: Cumberland, Frederick
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX) in patients with
active RA who have an inadequate response to MTX therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00406419?term=STAGE+AND+RA&rank=15
Additional information can be found here:
http://www.researchra.com/
"SCRIPT: Ocrelizumab Compared to Placebo in
Patients With Active Rheumatoid Arthritis Who Don't Have a Response to
Anti-TNF-A Therapy"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Baltimore, Wheaton
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX) or leflunomide,
given either alone or in combination with other non-biologic DMARDs in
patients with active RA who have an inadequate response to anti-TNF-A
therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00476996?term=SCRIPT&rank=3
Additional information can be found here:
http://www.researchra.com/
"PRECISION : Prospective Randomized Evaluation of Celecoxib Integrated Safety vs. Ibuprofen Or Naproxen"
Type(s) of arthritis being studied: Rheumatoid, osteoarthritis
Status of study: RECRUITING
Study sites can be found in: Columbia, Baltimore, Cumberland, Towson,
Rockville, Wheaton, Bowie, Frederick, Oxon Hill, Ayer, Fall River,
Northampton, Springfield, Worcester
Contact info: Pfizer CTgov Call Center, 1-800-718-1021
This study intends to study the risk of using celecoxib (i.e. Celebrex)
versus the use of NSAIDs for the treatment of arthritic pain. The focus
of risk will be on cardiovascular, gastrointestinal, and renal health.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00346216?order=2
"Safety and Effectiveness Study of
RWJ-445380 Cathepsin-S Inhibitor in Patients With Active Rheumatoid
Arthritis Despite Methotrexate Therapy"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Frederick
The purpose of this Phase II study is to evaluate the safety and
tolerability of 100, 200, and 300 mg/day doses of RWJ-445380 for up to
12 weeks in patients with active Rheumatoid Arthritis despite
methotrexate therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00425321?order=6
"Long-Term Effectiveness And Safety Of CP-690,550 For The Treatment Of Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Frederick
Contact info: Pfizer CTgov Call Center, 1-800-718-1021
The purpose of this study is to determine the long-term effectiveness
and safety of CP-690,550 for the treatment of rheumatoid arthritis.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00413699?order=12
Massachusetts
"STAGE: Ocrelizumab Compared to Placebo in Patients With Active Rheumatoid Arthritis Continuing Methotrexate Treatment"
Type(s) of arthritis being studied: Rheumatoid
Status of study: NO LONGER ENROLLING
Study sites can be found in: Worcester
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX) in patients with
active RA who have an inadequate response to MTX therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00406419?term=STAGE+AND+RA&rank=15
Additional information can be found here:
http://www.researchra.com/
"SCRIPT: Ocrelizumab Compared to Placebo in
Patients With Active Rheumatoid Arthritis Who Don't Have a Response to
Anti-TNF-A Therapy"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Worcester
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX) or leflunomide,
given either alone or in combination with other non-biologic DMARDs in
patients with active RA who have an inadequate response to anti-TNF-A
therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00476996?term=SCRIPT&rank=3
Additional information can be found here:
http://www.researchra.com/
"PRECISION : Prospective Randomized Evaluation of Celecoxib Integrated Safety vs. Ibuprofen Or Naproxen"
Type(s) of arthritis being studied: Rheumatoid, osteoarthritis
Status of study: RECRUITING
Study sites can be found in: Columbia, Baltimore, Cumberland, Towson,
Rockville, Wheaton, Bowie, Frederick, Oxon Hill, Ayer, Fall River,
Northampton, Springfield, Worcester
Contact info: Pfizer CTgov Call Center, 1-800-718-1021
This study intends to study the risk of using celecoxib (i.e. Celebrex)
versus the use of NSAIDs for the treatment of arthritic pain. The focus
of risk will be on cardiovascular, gastrointestinal, and renal health.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00346216?order=2
"Multiple Ascending Dose Study of BMS-582949 in Patients With Stable Rheumatoid Arthritis on the Methotrexate Background"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Fall River
This study intends to study the safety of taking methotrexate with BMS-582949.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00162292?order=3
"Treatment of Arthritis With Syk Kinase Inhibition (TASKI-1)"
Type(s) of arthritis being studied: rheumatoid
Status of study: RECRUITING
Study sites can be found in: Fall River
Contact info: Elliott Grossbard, M.D.; 650-624-1378, egrossbard@rigel.com
The goal of this study is to assess the preliminary efficacy of up to three different dosage regimens of R788.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00326339?order=7
Michigan
"TASKi: Treatment of Arthritis With Syk Kinase Inhibition"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Lansing
Contact info: http://www.taskistudy.com/Page.aspx?Page=Screen9
The TASKi study is composed of two studies.
(1)
A Phase II, Multicenter, Randomized, Double-Blind, Placebo-Controlled,
Parallel Dose Study of R935788 in Patients with Rheumatoid Arthritis
who have failed at least one biologic.
(2) A Phase II, Multicenter,
Randomized, Double-Blind, Placebo-Controlled, Parallel Dose Study of
Two Doses of R935788 in Rheumatoid Arthritis Patients Failing to
respond to Methotrexate.
Criteria for admittance and further information can be found here:
http://www.taskistudy.com/PreScreen.aspx
Additional information can be found here:
http://www.taskistudy.com
"FILM: The Safety and Efficacy of Ocrelizumab in Combination With Methotrexate in Patients With Active Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Ann Arbor, Kalamazoo
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX), compared with
methotrexate alone in patients with active RA of at least 3 months and
less than 5 years duration (and who are naive to MTX).
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00485589?term=FILM&rank=7
Additional information can be found here:
http://www.researchra.com/
"STAGE: Ocrelizumab Compared to Placebo in Patients With Active Rheumatoid Arthritis Continuing Methotrexate Treatment"
Type(s) of arthritis being studied: Rheumatoid
Status of study: NO LONGER ENROLLING
Study sites can be found in: Lansing, Kalamazoo, St. Clair Shores
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX) in patients with
active RA who have an inadequate response to MTX therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00406419?term=STAGE+AND+RA&rank=15
Additional information can be found here:
http://www.researchra.com/
"SCRIPT: Ocrelizumab Compared to Placebo in
Patients With Active Rheumatoid Arthritis Who Don't Have a Response to
Anti-TNF-A Therapy"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Lansing, Ann Arbor, Kalamazoo, St. Clair Shores
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX) or leflunomide,
given either alone or in combination with other non-biologic DMARDs in
patients with active RA who have an inadequate response to anti-TNF-A
therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00476996?term=SCRIPT&rank=3
Additional information can be found here:
http://www.researchra.com/
"PRECISION : Prospective Randomized Evaluation of Celecoxib Integrated Safety vs. Ibuprofen Or Naproxen"
Type(s) of arthritis being studied: Rheumatoid, osteoarthritis
Status of study: RECRUITING
Study sites can be found in: Cadillac, Troy, Lansing, Interlochen, Saginaw, Grand Rapids, St. Clair Shores
Contact info: Pfizer CTgov Call Center, 1-800-718-1021
This study intends to study the risk of using celecoxib (i.e. Celebrex)
versus the use of NSAIDs for the treatment of arthritic pain. The focus
of risk will be on cardiovascular, gastrointestinal, and renal health.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00346216?order=2
"Treatment of Arthritis With Syk Kinase Inhibition (TASKI-1)"
Type(s) of arthritis being studied: rheumatoid
Status of study: RECRUITING
Study sites can be found in: Brighton
Contact info: Elliott Grossbard, M.D.; 650-624-1378, egrossbard@rigel.com
The goal of this study is to assess the preliminary efficacy of up to three different dosage regimens of R788.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00326339?order=7
Minnesota
"FILM: The Safety and Efficacy of Ocrelizumab in Combination With Methotrexate in Patients With Active Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Eagan
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX), compared with
methotrexate alone in patients with active RA of at least 3 months and
less than 5 years duration (and who are naive to MTX).
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00485589?term=FILM&rank=7
Additional information can be found here:
http://www.researchra.com/
"STAGE: Ocrelizumab Compared to Placebo in Patients With Active Rheumatoid Arthritis Continuing Methotrexate Treatment"
Type(s) of arthritis being studied: Rheumatoid
Status of study: NO LONGER ENROLLING
Study sites can be found in: Duluth, Eagan, Minneapolis
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX) in patients with
active RA who have an inadequate response to MTX therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00406419?term=STAGE+AND+RA&rank=15
Additional information can be found here:
http://www.researchra.com/
"SCRIPT: Ocrelizumab Compared to Placebo in
Patients With Active Rheumatoid Arthritis Who Don't Have a Response to
Anti-TNF-A Therapy"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Duluth, Eagan, Minneapolis
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX) or leflunomide,
given either alone or in combination with other non-biologic DMARDs in
patients with active RA who have an inadequate response to anti-TNF-A
therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00476996?term=SCRIPT&rank=3
Additional information can be found here:
http://www.researchra.com/
"PRECISION : Prospective Randomized Evaluation of Celecoxib Integrated Safety vs. Ibuprofen Or Naproxen"
Type(s) of arthritis being studied: Rheumatoid, osteoarthritis
Status of study: RECRUITING
Study sites can be found in: Saint Cloud
Contact info: Pfizer CTgov Call Center, 1-800-718-1021
This study intends to study the risk of using celecoxib (i.e. Celebrex)
versus the use of NSAIDs for the treatment of arthritic pain. The focus
of risk will be on cardiovascular, gastrointestinal, and renal health.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00346216?order=2
Mississippi
"FILM: The Safety and Efficacy of Ocrelizumab in Combination With Methotrexate in Patients With Active Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Tupelo, Flowood
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX), compared with
methotrexate alone in patients with active RA of at least 3 months and
less than 5 years duration (and who are naive to MTX).
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00485589?term=FILM&rank=7
Additional information can be found here:
http://www.researchra.com/
"STAGE: Ocrelizumab Compared to Placebo in Patients With Active Rheumatoid Arthritis Continuing Methotrexate Treatment"
Type(s) of arthritis being studied: Rheumatoid
Status of study: NO LONGER ENROLLING
Study sites can be found in: Flowood
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX) in patients with
active RA who have an inadequate response to MTX therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00406419?term=STAGE+AND+RA&rank=15
Additional information can be found here:
http://www.researchra.com/
"SCRIPT: Ocrelizumab Compared to Placebo in
Patients With Active Rheumatoid Arthritis Who Don't Have a Response to
Anti-TNF-A Therapy"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Flowood, Tupelo
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX) or leflunomide,
given either alone or in combination with other non-biologic DMARDs in
patients with active RA who have an inadequate response to anti-TNF-A
therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00476996?term=SCRIPT&rank=3
Additional information can be found here:
http://www.researchra.com/
"PRECISION : Prospective Randomized Evaluation of Celecoxib Integrated Safety vs. Ibuprofen Or Naproxen"
Type(s) of arthritis being studied: Rheumatoid, osteoarthritis
Status of study: RECRUITING
Study sites can be found in: Port Gibson
Contact info: Pfizer CTgov Call Center, 1-800-718-1021
This study intends to study the risk of using celecoxib (i.e. Celebrex)
versus the use of NSAIDs for the treatment of arthritic pain. The focus
of risk will be on cardiovascular, gastrointestinal, and renal health.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00346216?order=2
Missouri
"FILM: The Safety and Efficacy of Ocrelizumab in Combination With Methotrexate in Patients With Active Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: St. Louis, Kansas City
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX), compared with
methotrexate alone in patients with active RA of at least 3 months and
less than 5 years duration (and who are naive to MTX).
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00485589?term=FILM&rank=7
Additional information can be found here:
http://www.researchra.com/
"STAGE: Ocrelizumab Compared to Placebo in Patients With Active Rheumatoid Arthritis Continuing Methotrexate Treatment"
Type(s) of arthritis being studied: Rheumatoid
Status of study: NO LONGER ENROLLING
Study sites can be found in: St. Louis, Florissant
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX) in patients with
active RA who have an inadequate response to MTX therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00406419?term=STAGE+AND+RA&rank=15
Additional information can be found here:
http://www.researchra.com/
"SCRIPT: Ocrelizumab Compared to Placebo in
Patients With Active Rheumatoid Arthritis Who Don't Have a Response to
Anti-TNF-A Therapy"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: St. Louis, Florissant, Springfield
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX) or leflunomide,
given either alone or in combination with other non-biologic DMARDs in
patients with active RA who have an inadequate response to anti-TNF-A
therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00476996?term=SCRIPT&rank=3
Additional information can be found here:
http://www.researchra.com/
"PRECISION : Prospective Randomized Evaluation of Celecoxib Integrated Safety vs. Ibuprofen Or Naproxen"
Type(s) of arthritis being studied: Rheumatoid, osteoarthritis
Status of study: RECRUITING
Study sites can be found in: Jefferson City, Springfield, Washington, St. Louis,
Contact info: Pfizer CTgov Call Center, 1-800-718-1021
This study intends to study the risk of using celecoxib (i.e. Celebrex)
versus the use of NSAIDs for the treatment of arthritic pain. The focus
of risk will be on cardiovascular, gastrointestinal, and renal health.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00346216?order=2
"Efficacy, Safety and Tolerability of ACZ885 in Patients With Active Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: St. Louis
Contact info: Novartis Pharmaceuticals New Jersey, United States, 1-862-778-8300
This Phase II study intends to collect long-term safety and
tolerability data with 300 mg of experimental drug ACZ885 in patients
with active rheumatoid arthritis (RA).
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00471198?order=2
"Efficacy, Safety and Tolerability of ACZ885 in Patients With Active Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: St. Louis
The purpose of this study is to evaluate risk-benefit of three
subcutaneous dose regimens of ACZ885, added on to stable methotrexate
therapy, compared to placebo in patients with active rheumatoid
arthritis.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00424346?order=7
Montana
"FILM: The Safety and Efficacy of Ocrelizumab in Combination With Methotrexate in Patients With Active Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Billings
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX), compared with
methotrexate alone in patients with active RA of at least 3 months and
less than 5 years duration (and who are naive to MTX).
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00485589?term=FILM&rank=7
Additional information can be found here:
http://www.researchra.com/
"PRECISION : Prospective Randomized Evaluation of Celecoxib Integrated Safety vs. Ibuprofen Or Naproxen"
Type(s) of arthritis being studied: Rheumatoid, osteoarthritis
Status of study: RECRUITING
Study sites can be found in: Kalispell
Contact info: Pfizer CTgov Call Center, 1-800-718-1021
This study intends to study the risk of using celecoxib (i.e. Celebrex)
versus the use of NSAIDs for the treatment of arthritic pain. The focus
of risk will be on cardiovascular, gastrointestinal, and renal health.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00346216?order=2
Nebraska
"TASKi: Treatment of Arthritis With Syk Kinase Inhibition"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Omaha
Contact info: http://www.taskistudy.com/Page.aspx?Page=Screen9
The TASKi study is composed of two studies.
(1)
A Phase II, Multicenter, Randomized, Double-Blind, Placebo-Controlled,
Parallel Dose Study of R935788 in Patients with Rheumatoid Arthritis
who have failed at least one biologic.
(2) A Phase II, Multicenter,
Randomized, Double-Blind, Placebo-Controlled, Parallel Dose Study of
Two Doses of R935788 in Rheumatoid Arthritis Patients Failing to
respond to Methotrexate.
Criteria for admittance and further information can be found here:
http://www.taskistudy.com/PreScreen.aspx
Additional information can be found here:
http://www.taskistudy.com
"FILM: The Safety and Efficacy of Ocrelizumab in Combination With Methotrexate in Patients With Active Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Lincoln
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX), compared with
methotrexate alone in patients with active RA of at least 3 months and
less than 5 years duration (and who are naive to MTX).
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00485589?term=FILM&rank=7
Additional information can be found here:
http://www.researchra.com/
"STAGE: Ocrelizumab Compared to Placebo in Patients With Active Rheumatoid Arthritis Continuing Methotrexate Treatment"
Type(s) of arthritis being studied: Rheumatoid
Status of study: NO LONGER ENROLLING
Study sites can be found in: Omaha
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX) in patients with
active RA who have an inadequate response to MTX therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00406419?term=STAGE+AND+RA&rank=15
Additional information can be found here:
http://www.researchra.com/
"SCRIPT: Ocrelizumab Compared to Placebo in
Patients With Active Rheumatoid Arthritis Who Don't Have a Response to
Anti-TNF-A Therapy"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Omaha
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX) or leflunomide,
given either alone or in combination with other non-biologic DMARDs in
patients with active RA who have an inadequate response to anti-TNF-A
therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00476996?term=SCRIPT&rank=3
Additional information can be found here:
http://www.researchra.com/
"PRECISION : Prospective Randomized Evaluation of Celecoxib Integrated Safety vs. Ibuprofen Or Naproxen"
Type(s) of arthritis being studied: Rheumatoid, osteoarthritis
Status of study: RECRUITING
Study sites can be found in: Omaha, Alliance, North Platte
Contact info: Pfizer CTgov Call Center, 1-800-718-1021
This study intends to study the risk of using celecoxib (i.e. Celebrex)
versus the use of NSAIDs for the treatment of arthritic pain. The focus
of risk will be on cardiovascular, gastrointestinal, and renal health.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00346216?order=2
"Treatment of Arthritis With Syk Kinase Inhibition (TASKI-1)"
Type(s) of arthritis being studied: rheumatoid
Status of study: RECRUITING
Study sites can be found in: Omaha
Contact info: Elliott Grossbard, M.D.; 650-624-1378, egrossbard@rigel.com
The goal of this study is to assess the preliminary efficacy of up to three different dosage regimens of R788.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00326339?order=7
"A Phase 2 Study to Evaluate the Efficacy and Safety of 60mg of MM-093 in Patients With Active Rheumatoid Arthritis"
Type(s) of arthritis being studied: rheumatoid
Status of study: RECRUITING
Study sites can be found in: Lincoln
Contact info: Jayne Belanger; 978-568-8880, jbelanger@clinquestinc.com
The purpose of this study is to determine whether MM-093 is safe and
effective in the treatment of rheumatoid arthritis.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00458146?order=10
Nevada
"FILM: The Safety and Efficacy of Ocrelizumab in Combination With Methotrexate in Patients With Active Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Las Vegas, Reno
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX), compared with
methotrexate alone in patients with active RA of at least 3 months and
less than 5 years duration (and who are naive to MTX).
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00485589?term=FILM&rank=7
Additional information can be found here:
http://www.researchra.com/
"STAGE: Ocrelizumab Compared to Placebo in Patients With Active Rheumatoid Arthritis Continuing Methotrexate Treatment"
Type(s) of arthritis being studied: Rheumatoid
Status of study: NO LONGER ENROLLING
Study sites can be found in: Reno
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX) in patients with
active RA who have an inadequate response to MTX therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00406419?term=STAGE+AND+RA&rank=15
Additional information can be found here:
http://www.researchra.com/
"PRECISION : Prospective Randomized Evaluation of Celecoxib Integrated Safety vs. Ibuprofen Or Naproxen"
Type(s) of arthritis being studied: Rheumatoid, osteoarthritis
Status of study: RECRUITING
Study sites can be found in: Reno, Las Vegas, Incline Village
Contact info: Pfizer CTgov Call Center, 1-800-718-1021
This study intends to study the risk of using celecoxib (i.e. Celebrex)
versus the use of NSAIDs for the treatment of arthritic pain. The focus
of risk will be on cardiovascular, gastrointestinal, and renal health.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00346216?order=2
"Treatment of Arthritis With Syk Kinase Inhibition (TASKI-1)"
Type(s) of arthritis being studied: rheumatoid
Status of study: RECRUITING
Study sites can be found in: Raleigh
Contact info: Elliott Grossbard, M.D.; 650-624-1378, egrossbard@rigel.com
The goal of this study is to assess the preliminary efficacy of up to three different dosage regimens of R788.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00326339?order=7
New Hampshire
"SCRIPT: Ocrelizumab Compared to Placebo in
Patients With Active Rheumatoid Arthritis Who Don't Have a Response to
Anti-TNF-A Therapy"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Nashua, Dover
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX) or leflunomide,
given either alone or in combination with other non-biologic DMARDs in
patients with active RA who have an inadequate response to anti-TNF-A
therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00476996?term=SCRIPT&rank=3
Additional information can be found here:
http://www.researchra.com/
"A Phase 2 Study to Evaluate the Efficacy and Safety of 60mg of MM-093 in Patients With Active Rheumatoid Arthritis"
Type(s) of arthritis being studied: rheumatoid
Status of study: RECRUITING
Study sites can be found in: Concord
Contact info: Jayne Belanger; 978-568-8880, jbelanger@clinquestinc.com
The purpose of this study is to determine whether MM-093 is safe and
effective in the treatment of rheumatoid arthritis.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00458146?order=10
New Jersey
"STAGE: Ocrelizumab Compared to Placebo in Patients With Active Rheumatoid Arthritis Continuing Methotrexate Treatment"
Type(s) of arthritis being studied: Rheumatoid
Status of study: NO LONGER ENROLLING
Study sites can be found in: Haddon Heights
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX) in patients with
active RA who have an inadequate response to MTX therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00406419?term=STAGE+AND+RA&rank=15
Additional information can be found here:
http://www.researchra.com/
"SCRIPT: Ocrelizumab Compared to Placebo in
Patients With Active Rheumatoid Arthritis Who Don't Have a Response to
Anti-TNF-A Therapy"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Haddon Heights, Voorhees
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX) or leflunomide,
given either alone or in combination with other non-biologic DMARDs in
patients with active RA who have an inadequate response to anti-TNF-A
therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00476996?term=SCRIPT&rank=3
Additional information can be found here:
http://www.researchra.com/
"PRECISION : Prospective Randomized Evaluation of Celecoxib Integrated Safety vs. Ibuprofen Or Naproxen"
Type(s) of arthritis being studied: Rheumatoid, osteoarthritis
Status of study: RECRUITING
Study sites can be found in: Clifton, Hamilton Township, Trenton, Brown
Mills, Edison, Haddon Heights, Medford, Elizabeth, Hazlet
Contact info: Pfizer CTgov Call Center, 1-800-718-1021
This study intends to study the risk of using celecoxib (i.e. Celebrex)
versus the use of NSAIDs for the treatment of arthritic pain. The focus
of risk will be on cardiovascular, gastrointestinal, and renal health.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00346216?order=2
New Mexico
"FILM: The Safety and Efficacy of Ocrelizumab in Combination With Methotrexate in Patients With Active Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Albuquerque
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX), compared with
methotrexate alone in patients with active RA of at least 3 months and
less than 5 years duration (and who are naive to MTX).
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00485589?term=FILM&rank=7
Additional information can be found here:
http://www.researchra.com/
"A Safety and Pharmacokinetics Study in Patients With Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Albuquerque
Contact info: 1-877-285-4559 or 1-317-615-4559
The purpose of this study is to examine the safety and tolerability of the LY2189102 antibody in rheumatoid arthritis patients.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00380744?order=15
New York
"FILM: The Safety and Efficacy of Ocrelizumab in Combination With Methotrexate in Patients With Active Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Olean
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX), compared with
methotrexate alone in patients with active RA of at least 3 months and
less than 5 years duration (and who are naive to MTX).
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00485589?term=FILM&rank=7
Additional information can be found here:
http://www.researchra.com/
"STAGE: Ocrelizumab Compared to Placebo in Patients With Active Rheumatoid Arthritis Continuing Methotrexate Treatment"
Type(s) of arthritis being studied: Rheumatoid
Status of study: NO LONGER ENROLLING
Study sites can be found in: Plainview, Lake Success, Brooklyn, Albany, Rochester, Syracuse, Olean
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX) in patients with
active RA who have an inadequate response to MTX therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00406419?term=STAGE+AND+RA&rank=15
Additional information can be found here:
http://www.researchra.com/
"SCRIPT: Ocrelizumab Compared to Placebo in
Patients With Active Rheumatoid Arthritis Who Don't Have a Response to
Anti-TNF-A Therapy"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Rochester, Brooklyn, Smithtown, Albany, Roslyn
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX) or leflunomide,
given either alone or in combination with other non-biologic DMARDs in
patients with active RA who have an inadequate response to anti-TNF-A
therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00476996?term=SCRIPT&rank=3
Additional information can be found here:
http://www.researchra.com/
"PRECISION : Prospective Randomized Evaluation of Celecoxib Integrated Safety vs. Ibuprofen Or Naproxen"
Type(s) of arthritis being studied: Rheumatoid, osteoarthritis
Status of study: RECRUITING
Study sites can be found in: West Seneca, Westfield, Johnson City,
Great Neck, Elmira, Williamsville, Rochester, Mamaroneck, Brooklyn,
Smithtown, Roslyn, Poughkeepsie, Wantagh, Dunkirk, Syosset
Contact info: Pfizer CTgov Call Center, 1-800-718-1021
This study intends to study the risk of using celecoxib (i.e. Celebrex)
versus the use of NSAIDs for the treatment of arthritic pain. The focus
of risk will be on cardiovascular, gastrointestinal, and renal health.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00346216?order=2
"Efficacy, Safety and Tolerability of ACZ885 in Patients With Active Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Albany
Contact info: Novartis Pharmaceuticals New Jersey, United States, 1-862-778-8300
This Phase II study intends to collect long-term safety and
tolerability data with 300 mg of experimental drug ACZ885 in patients
with active rheumatoid arthritis (RA).
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00471198?order=2
"Efficacy, Safety and Tolerability of ACZ885 in Patients With Active Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Albany, Rochester
The purpose of this study is to evaluate risk-benefit of three
subcutaneous dose regimens of ACZ885, added on to stable methotrexate
therapy, compared to placebo in patients with active rheumatoid
arthritis.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00424346?order=7
"Long-Term Effectiveness And Safety Of CP-690,550 For The Treatment Of Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Albany
Contact info: Pfizer CTgov Call Center, 1-800-718-1021
The purpose of this study is to determine the long-term effectiveness
and safety of CP-690,550 for the treatment of rheumatoid arthritis.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00413699?order=12
North Carolina
"TASKi: Treatment of Arthritis With Syk Kinase Inhibition"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Raleigh
Contact info: http://www.taskistudy.com/Page.aspx?Page=Screen9
The TASKi study is composed of two studies.
(1)
A Phase II, Multicenter, Randomized, Double-Blind, Placebo-Controlled,
Parallel Dose Study of R935788 in Patients with Rheumatoid Arthritis
who have failed at least one biologic.
(2) A Phase II, Multicenter,
Randomized, Double-Blind, Placebo-Controlled, Parallel Dose Study of
Two Doses of R935788 in Rheumatoid Arthritis Patients Failing to
respond to Methotrexate.
Criteria for admittance and further information can be found here:
http://www.taskistudy.com/PreScreen.aspx
Additional information can be found here:
http://www.taskistudy.com
"FILM: The Safety and Efficacy of Ocrelizumab in Combination With Methotrexate in Patients With Active Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Hickory, Charlotte, Belmont, Greenville
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX), compared with
methotrexate alone in patients with active RA of at least 3 months and
less than 5 years duration (and who are naive to MTX).
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00485589?term=FILM&rank=7
Additional information can be found here:
http://www.researchra.com/
"STAGE: Ocrelizumab Compared to Placebo in Patients With Active Rheumatoid Arthritis Continuing Methotrexate Treatment"
Type(s) of arthritis being studied: Rheumatoid
Status of study: NO LONGER ENROLLING
Study sites can be found in: Asheville, Charlotte, Greenville, Belmont
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX) in patients with
active RA who have an inadequate response to MTX therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00406419?term=STAGE+AND+RA&rank=15
Additional information can be found here:
http://www.researchra.com/
"SCRIPT: Ocrelizumab Compared to Placebo in
Patients With Active Rheumatoid Arthritis Who Don't Have a Response to
Anti-TNF-A Therapy"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Charlotte, Asheville, Belmont, Hickory
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX) or leflunomide,
given either alone or in combination with other non-biologic DMARDs in
patients with active RA who have an inadequate response to anti-TNF-A
therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00476996?term=SCRIPT&rank=3
Additional information can be found here:
http://www.researchra.com/
"PRECISION : Prospective Randomized Evaluation of Celecoxib Integrated Safety vs. Ibuprofen Or Naproxen"
Type(s) of arthritis being studied: Rheumatoid, osteoarthritis
Status of study: RECRUITING
Study sites can be found in: Winston-Salem, Asheville, Charlotte, Cary, Rocky Mount, Salisbury, Raleigh, Tabor City
Contact info: Pfizer CTgov Call Center, 1-800-718-1021
This study intends to study the risk of using celecoxib (i.e. Celebrex)
versus the use of NSAIDs for the treatment of arthritic pain. The focus
of risk will be on cardiovascular, gastrointestinal, and renal health.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00346216?order=2
"A Phase 2 Study to Evaluate the Efficacy and Safety of 60mg of MM-093 in Patients With Active Rheumatoid Arthritis"
Type(s) of arthritis being studied: rheumatoid
Status of study: RECRUITING
Study sites can be found in: Charlotte
Contact info: Jayne Belanger; 978-568-8880, jbelanger@clinquestinc.com
The purpose of this study is to determine whether MM-093 is safe and
effective in the treatment of rheumatoid arthritis.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00458146?order=10
"Long-Term Effectiveness And Safety Of CP-690,550 For The Treatment Of Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Charlotte
Contact info: Pfizer CTgov Call Center, 1-800-718-1021
The purpose of this study is to determine the long-term effectiveness
and safety of CP-690,550 for the treatment of rheumatoid arthritis.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00413699?order=12
North Dakota
"FILM: The Safety and Efficacy of Ocrelizumab in Combination With Methotrexate in Patients With Active Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Bismarck
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX), compared with
methotrexate alone in patients with active RA of at least 3 months and
less than 5 years duration (and who are naive to MTX).
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00485589?term=FILM&rank=7
Additional information can be found here:
http://www.researchra.com/
"SCRIPT: Ocrelizumab Compared to Placebo in
Patients With Active Rheumatoid Arthritis Who Don't Have a Response to
Anti-TNF-A Therapy"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Bismarck
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX) or leflunomide,
given either alone or in combination with other non-biologic DMARDs in
patients with active RA who have an inadequate response to anti-TNF-A
therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00476996?term=SCRIPT&rank=3
Additional information can be found here:
http://www.researchra.com/
"PRECISION : Prospective Randomized Evaluation of Celecoxib Integrated Safety vs. Ibuprofen Or Naproxen"
Type(s) of arthritis being studied: Rheumatoid, osteoarthritis
Status of study: RECRUITING
Study sites can be found in: Fargo
Contact info: Pfizer CTgov Call Center, 1-800-718-1021
This study intends to study the risk of using celecoxib (i.e. Celebrex)
versus the use of NSAIDs for the treatment of arthritic pain. The focus
of risk will be on cardiovascular, gastrointestinal, and renal health.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00346216?order=2
Ohio
"TASKi: Treatment of Arthritis With Syk Kinase Inhibition"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Mayfield Village, Gallipolis, and Cleveland
Contact info: http://www.taskistudy.com/Page.aspx?Page=Screen9
The TASKi study is composed of two studies.
(1)
A Phase II, Multicenter, Randomized, Double-Blind, Placebo-Controlled,
Parallel Dose Study of R935788 in Patients with Rheumatoid Arthritis
who have failed at least one biologic.
(2) A Phase II, Multicenter,
Randomized, Double-Blind, Placebo-Controlled, Parallel Dose Study of
Two Doses of R935788 in Rheumatoid Arthritis Patients Failing to
respond to Methotrexate.
Criteria for admittance and further information can be found here:
http://www.taskistudy.com/PreScreen.aspx
Additional information can be found here:
http://www.taskistudy.com
"FILM: The Safety and Efficacy of Ocrelizumab in Combination With Methotrexate in Patients With Active Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Middleburg Heights, Chardon
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX), compared with
methotrexate alone in patients with active RA of at least 3 months and
less than 5 years duration (and who are naive to MTX).
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00485589?term=FILM&rank=7
Additional information can be found here:
http://www.researchra.com/
"STAGE: Ocrelizumab Compared to Placebo in Patients With Active Rheumatoid Arthritis Continuing Methotrexate Treatment"
Type(s) of arthritis being studied: Rheumatoid
Status of study: NO LONGER ENROLLING
Study sites can be found in: Cincinnati, Mayfield Village, Beachwood, Dayton
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX) in patients with
active RA who have an inadequate response to MTX therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00406419?term=STAGE+AND+RA&rank=15
Additional information can be found here:
http://www.researchra.com/
"SCRIPT: Ocrelizumab Compared to Placebo in
Patients With Active Rheumatoid Arthritis Who Don't Have a Response to
Anti-TNF-A Therapy"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Middleburg Heights, Cincinnati, Mayfield Village, Beachwood, Dayton
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX) or leflunomide,
given either alone or in combination with other non-biologic DMARDs in
patients with active RA who have an inadequate response to anti-TNF-A
therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00476996?term=SCRIPT&rank=3
Additional information can be found here:
http://www.researchra.com/
"PRECISION : Prospective Randomized Evaluation of Celecoxib Integrated Safety vs. Ibuprofen Or Naproxen"
Type(s) of arthritis being studied: Rheumatoid, osteoarthritis
Status of study: RECRUITING
Study sites can be found in: Columbus, London, Zanesville, Mansfield, Perrysburg, Mayfield Village, Fairview Park, Franklin
Contact info: Pfizer CTgov Call Center, 1-800-718-1021
This study intends to study the risk of using celecoxib (i.e. Celebrex)
versus the use of NSAIDs for the treatment of arthritic pain. The focus
of risk will be on cardiovascular, gastrointestinal, and renal health.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00346216?order=2
"Treatment of Arthritis With Syk Kinase Inhibition (TASKI-1)"
Type(s) of arthritis being studied: rheumatoid
Status of study: RECRUITING
Study sites can be found in: Mayfield Village
Contact info: Elliott Grossbard, M.D.; 650-624-1378, egrossbard@rigel.com
The goal of this study is to assess the preliminary efficacy of up to three different dosage regimens of R788.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00326339?order=7
"Long-Term Effectiveness And Safety Of CP-690,550 For The Treatment Of Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Dayton
Contact info: Pfizer CTgov Call Center, 1-800-718-1021
The purpose of this study is to determine the long-term effectiveness
and safety of CP-690,550 for the treatment of rheumatoid arthritis.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00413699?order=12
"A Safety and Pharmacokinetics Study in Patients With Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Mayfield Village
Contact info: 1-877-285-4559 or 1-317-615-4559
The purpose of this study is to examine the safety and tolerability of the LY2189102 antibody in rheumatoid arthritis patients.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00380744?order=15
Oklahoma
"TASKi: Treatment of Arthritis With Syk Kinase Inhibition"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Oklahoma City
Contact info: http://www.taskistudy.com/Page.aspx?Page=Screen9
The TASKi study is composed of two studies.
(1)
A Phase II, Multicenter, Randomized, Double-Blind, Placebo-Controlled,
Parallel Dose Study of R935788 in Patients with Rheumatoid Arthritis
who have failed at least one biologic.
(2) A Phase II, Multicenter,
Randomized, Double-Blind, Placebo-Controlled, Parallel Dose Study of
Two Doses of R935788 in Rheumatoid Arthritis Patients Failing to
respond to Methotrexate.
Criteria for admittance and further information can be found here:
http://www.taskistudy.com/PreScreen.aspx
Additional information can be found here:
http://www.taskistudy.com
"FILM: The Safety and Efficacy of Ocrelizumab in Combination With Methotrexate in Patients With Active Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Oklahoma City, Tulsa
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX), compared with
methotrexate alone in patients with active RA of at least 3 months and
less than 5 years duration (and who are naive to MTX).
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00485589?term=FILM&rank=7
Additional information can be found here:
http://www.researchra.com/
"STAGE: Ocrelizumab Compared to Placebo in Patients With Active Rheumatoid Arthritis Continuing Methotrexate Treatment"
Type(s) of arthritis being studied: Rheumatoid
Status of study: NO LONGER ENROLLING
Study sites can be found in: Oklahoma City, Tulsa
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX) in patients with
active RA who have an inadequate response to MTX therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00406419?term=STAGE+AND+RA&rank=15
Additional information can be found here:
http://www.researchra.com/
"SCRIPT: Ocrelizumab Compared to Placebo in
Patients With Active Rheumatoid Arthritis Who Don't Have a Response to
Anti-TNF-A Therapy"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Oklahoma City, Tulsa
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX) or leflunomide,
given either alone or in combination with other non-biologic DMARDs in
patients with active RA who have an inadequate response to anti-TNF-A
therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00476996?term=SCRIPT&rank=3
Additional information can be found here:
http://www.researchra.com/
"PRECISION : Prospective Randomized Evaluation of Celecoxib Integrated Safety vs. Ibuprofen Or Naproxen"
Type(s) of arthritis being studied: Rheumatoid, osteoarthritis
Status of study: RECRUITING
Study sites can be found in: Norman, Oklahoma City
Contact info: Pfizer CTgov Call Center, 1-800-718-1021
This study intends to study the risk of using celecoxib (i.e. Celebrex)
versus the use of NSAIDs for the treatment of arthritic pain. The focus
of risk will be on cardiovascular, gastrointestinal, and renal health.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00346216?order=2
"Treatment of Arthritis With Syk Kinase Inhibition (TASKI-1)"
Type(s) of arthritis being studied: rheumatoid
Status of study: RECRUITING
Study sites can be found in: Oklahoma City
Contact info: Elliott Grossbard, M.D.; 650-624-1378, egrossbard@rigel.com
The goal of this study is to assess the preliminary efficacy of up to three different dosage regimens of R788.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00326339?order=7
Oregon
"FILM: The Safety and Efficacy of Ocrelizumab in Combination With Methotrexate in Patients With Active Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Lake Oswego
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX), compared with
methotrexate alone in patients with active RA of at least 3 months and
less than 5 years duration (and who are naive to MTX).
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00485589?term=FILM&rank=7
Additional information can be found here:
http://www.researchra.com/
"STAGE: Ocrelizumab Compared to Placebo in Patients With Active Rheumatoid Arthritis Continuing Methotrexate Treatment"
Type(s) of arthritis being studied: Rheumatoid
Status of study: NO LONGER ENROLLING
Study sites can be found in: Portland, Eugene, Bend
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX) in patients with
active RA who have an inadequate response to MTX therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00406419?term=STAGE+AND+RA&rank=15
Additional information can be found here:
http://www.researchra.com/
"SCRIPT: Ocrelizumab Compared to Placebo in
Patients With Active Rheumatoid Arthritis Who Don't Have a Response to
Anti-TNF-A Therapy"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Lake Oswego, Eugene, Bend
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX) or leflunomide,
given either alone or in combination with other non-biologic DMARDs in
patients with active RA who have an inadequate response to anti-TNF-A
therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00476996?term=SCRIPT&rank=3
Additional information can be found here:
http://www.researchra.com/
"PRECISION : Prospective Randomized Evaluation of Celecoxib Integrated Safety vs. Ibuprofen Or Naproxen"
Type(s) of arthritis being studied: Rheumatoid, osteoarthritis
Status of study: RECRUITING
Study sites can be found in: Portland, Eugene, Medford
Contact info: Pfizer CTgov Call Center, 1-800-718-1021
This study intends to study the risk of using celecoxib (i.e. Celebrex)
versus the use of NSAIDs for the treatment of arthritic pain. The focus
of risk will be on cardiovascular, gastrointestinal, and renal health.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00346216?order=2
"Efficacy, Safety and Tolerability of ACZ885 in Patients With Active Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Portland
Contact info: Novartis Pharmaceuticals New Jersey, United States, 1-862-778-8300
This Phase II study intends to collect long-term safety and
tolerability data with 300 mg of experimental drug ACZ885 in patients
with active rheumatoid arthritis (RA).
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00471198?order=2
"Efficacy, Safety and Tolerability of ACZ885 in Patients With Active Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Portland
The purpose of this study is to evaluate risk-benefit of three
subcutaneous dose regimens of ACZ885, added on to stable methotrexate
therapy, compared to placebo in patients with active rheumatoid
arthritis.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00424346?order=7
"A Safety and Pharmacokinetics Study in Patients With Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Bend
Contact info: 1-877-285-4559 or 1-317-615-4559
The purpose of this study is to examine the safety and tolerability of the LY2189102 antibody in rheumatoid arthritis patients.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00380744?order=15
Pennsylvania
"TASKi: Treatment of Arthritis With Syk Kinase Inhibition"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Philadelphia, Reading, West Reading, and Erie
Contact info: http://www.taskistudy.com/Page.aspx?Page=Screen9
The TASKi study is composed of two studies.
(1)
A Phase II, Multicenter, Randomized, Double-Blind, Placebo-Controlled,
Parallel Dose Study of R935788 in Patients with Rheumatoid Arthritis
who have failed at least one biologic.
(2) A Phase II, Multicenter,
Randomized, Double-Blind, Placebo-Controlled, Parallel Dose Study of
Two Doses of R935788 in Rheumatoid Arthritis Patients Failing to
respond to Methotrexate.
Criteria for admittance and further information can be found here:
http://www.taskistudy.com/PreScreen.aspx
Additional information can be found here:
http://www.taskistudy.com
"FILM: The Safety and Efficacy of Ocrelizumab in Combination With Methotrexate in Patients With Active Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Duncansville, Wexford, Philadelphia
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX), compared with
methotrexate alone in patients with active RA of at least 3 months and
less than 5 years duration (and who are naive to MTX).
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00485589?term=FILM&rank=7
Additional information can be found here:
http://www.researchra.com/
"STAGE: Ocrelizumab Compared to Placebo in Patients With Active Rheumatoid Arthritis Continuing Methotrexate Treatment"
Type(s) of arthritis being studied: Rheumatoid
Status of study: NO LONGER ENROLLING
Study sites can be found in: West Reading, Duncansville, Allentown, Bethlehem
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX) in patients with
active RA who have an inadequate response to MTX therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00406419?term=STAGE+AND+RA&rank=15
Additional information can be found here:
http://www.researchra.com/
"SCRIPT: Ocrelizumab Compared to Placebo in
Patients With Active Rheumatoid Arthritis Who Don't Have a Response to
Anti-TNF-A Therapy"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Erie, West Reading, Bethlehem, Wexford, Philadelphia
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX) or leflunomide,
given either alone or in combination with other non-biologic DMARDs in
patients with active RA who have an inadequate response to anti-TNF-A
therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00476996?term=SCRIPT&rank=3
Additional information can be found here:
http://www.researchra.com/
"PRECISION : Prospective Randomized Evaluation of Celecoxib Integrated Safety vs. Ibuprofen Or Naproxen"
Type(s) of arthritis being studied: Rheumatoid, osteoarthritis
Status of study: RECRUITING
Study sites can be found in: Camp Hill, West Reading, Duncansville,
Bethlehem, Beaver, Lansdale, Yardley, Red Lion, Buckingham, Erie,
Stoneboro, Huntingville, Philadelphia, Harleysville, Downingtown,
Chicora, Collegeville, Sellersville, Colmar, Feasterville, Scotland,
Wexford, Springfield
Contact info: Pfizer CTgov Call Center, 1-800-718-1021
This study intends to study the risk of using celecoxib (i.e. Celebrex)
versus the use of NSAIDs for the treatment of arthritic pain. The focus
of risk will be on cardiovascular, gastrointestinal, and renal health.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00346216?order=2
"Safety and Effectiveness Study of
RWJ-445380 Cathepsin-S Inhibitor in Patients With Active Rheumatoid
Arthritis Despite Methotrexate Therapy"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Duncansville
The purpose of this Phase II study is to evaluate the safety and
tolerability of 100, 200, and 300 mg/day doses of RWJ-445380 for up to
12 weeks in patients with active Rheumatoid Arthritis despite
methotrexate therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00425321?order=6
"Treatment of Arthritis With Syk Kinase Inhibition (TASKI-1)"
Type(s) of arthritis being studied: rheumatoid
Status of study: RECRUITING
Study sites can be found in: Bethlehem, Duncansville, West Reading
Contact info: Elliott Grossbard, M.D.; 650-624-1378, egrossbard@rigel.com
The goal of this study is to assess the preliminary efficacy of up to three different dosage regimens of R788.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00326339?order=7
"A Phase 2 Study to Evaluate the Efficacy and Safety of 60mg of MM-093 in Patients With Active Rheumatoid Arthritis"
Type(s) of arthritis being studied: rheumatoid
Status of study: RECRUITING
Study sites can be found in: Duncansville
Contact info: Jayne Belanger; 978-568-8880, jbelanger@clinquestinc.com
The purpose of this study is to determine whether MM-093 is safe and
effective in the treatment of rheumatoid arthritis.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00458146?order=10
"Long-Term Effectiveness And Safety Of CP-690,550 For The Treatment Of Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Philadelphia, West Reading
Contact info: Pfizer CTgov Call Center, 1-800-718-1021
The purpose of this study is to determine the long-term effectiveness
and safety of CP-690,550 for the treatment of rheumatoid arthritis.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00413699?order=12
"A Safety and Pharmacokinetics Study in Patients With Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Wexford
Contact info: 1-877-285-4559 or 1-317-615-4559
The purpose of this study is to examine the safety and tolerability of the LY2189102 antibody in rheumatoid arthritis patients.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00380744?order=15
Rhode Island
"PRECISION : Prospective Randomized Evaluation of Celecoxib Integrated Safety vs. Ibuprofen Or Naproxen"
Type(s) of arthritis being studied: Rheumatoid, osteoarthritis
Status of study: RECRUITING
Study sites can be found in: Cumberland, Cranston, Providence
Contact info: Pfizer CTgov Call Center, 1-800-718-1021
This study intends to study the risk of using celecoxib (i.e. Celebrex)
versus the use of NSAIDs for the treatment of arthritic pain. The focus
of risk will be on cardiovascular, gastrointestinal, and renal health.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00346216?order=2
South Carolina
"TASKi: Treatment of Arthritis With Syk Kinase Inhibition"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Charleston
Contact info: http://www.taskistudy.com/Page.aspx?Page=Screen9
The TASKi study is composed of two studies.
(1)
A Phase II, Multicenter, Randomized, Double-Blind, Placebo-Controlled,
Parallel Dose Study of R935788 in Patients with Rheumatoid Arthritis
who have failed at least one biologic.
(2) A Phase II, Multicenter,
Randomized, Double-Blind, Placebo-Controlled, Parallel Dose Study of
Two Doses of R935788 in Rheumatoid Arthritis Patients Failing to
respond to Methotrexate.
Criteria for admittance and further information can be found here:
http://www.taskistudy.com/PreScreen.aspx
Additional information can be found here:
http://www.taskistudy.com
"STAGE: Ocrelizumab Compared to Placebo in Patients With Active Rheumatoid Arthritis Continuing Methotrexate Treatment"
Type(s) of arthritis being studied: Rheumatoid
Status of study: NO LONGER ENROLLING
Study sites can be found in: Charleston, Greenville
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX) in patients with
active RA who have an inadequate response to MTX therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00406419?term=STAGE+AND+RA&rank=15
Additional information can be found here:
http://www.researchra.com/
"SCRIPT: Ocrelizumab Compared to Placebo in
Patients With Active Rheumatoid Arthritis Who Don't Have a Response to
Anti-TNF-A Therapy"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Charleston, Spartanburg, Greenville
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX) or leflunomide,
given either alone or in combination with other non-biologic DMARDs in
patients with active RA who have an inadequate response to anti-TNF-A
therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00476996?term=SCRIPT&rank=3
Additional information can be found here:
http://www.researchra.com/
"PRECISION : Prospective Randomized Evaluation of Celecoxib Integrated Safety vs. Ibuprofen Or Naproxen"
Type(s) of arthritis being studied: Rheumatoid, osteoarthritis
Status of study: RECRUITING
Study sites can be found in: Summerville, Greer, Columbia, Charleston, Mt. Pleasant
Contact info: Pfizer CTgov Call Center, 1-800-718-1021
This study intends to study the risk of using celecoxib (i.e. Celebrex)
versus the use of NSAIDs for the treatment of arthritic pain. The focus
of risk will be on cardiovascular, gastrointestinal, and renal health.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00346216?order=2
"Treatment of Arthritis With Syk Kinase Inhibition (TASKI-1)"
Type(s) of arthritis being studied: rheumatoid
Status of study: RECRUITING
Study sites can be found in: Charleston
Contact info: Elliott Grossbard, M.D.; 650-624-1378, egrossbard@rigel.com
The goal of this study is to assess the preliminary efficacy of up to three different dosage regimens of R788.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00326339?order=7
"Long-Term Effectiveness And Safety Of CP-690,550 For The Treatment Of Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Greenville
Contact info: Pfizer CTgov Call Center, 1-800-718-1021
The purpose of this study is to determine the long-term effectiveness
and safety of CP-690,550 for the treatment of rheumatoid arthritis.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00413699?order=12
"A Safety and Pharmacokinetics Study in Patients With Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Orangeburg
Contact info: 1-877-285-4559 or 1-317-615-4559
The purpose of this study is to examine the safety and tolerability of the LY2189102 antibody in rheumatoid arthritis patients.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00380744?order=15
South Dakota
"PRECISION : Prospective Randomized Evaluation of Celecoxib Integrated Safety vs. Ibuprofen Or Naproxen"
Type(s) of arthritis being studied: Rheumatoid, osteoarthritis
Status of study: RECRUITING
Study sites can be found in: Rapid City, Watertown, Aberdeen
Contact info: Pfizer CTgov Call Center, 1-800-718-1021
This study intends to study the risk of using celecoxib (i.e. Celebrex)
versus the use of NSAIDs for the treatment of arthritic pain. The focus
of risk will be on cardiovascular, gastrointestinal, and renal health.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00346216?order=2
Tennessee
"FILM: The Safety and Efficacy of Ocrelizumab in Combination With Methotrexate in Patients With Active Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Jackson, Memphis
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX), compared with
methotrexate alone in patients with active RA of at least 3 months and
less than 5 years duration (and who are naive to MTX).
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00485589?term=FILM&rank=7
Additional information can be found here:
http://www.researchra.com/
"STAGE: Ocrelizumab Compared to Placebo in Patients With Active Rheumatoid Arthritis Continuing Methotrexate Treatment"
Type(s) of arthritis being studied: Rheumatoid
Status of study: NO LONGER ENROLLING
Study sites can be found in: Memphis, Jackson
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX) in patients with
active RA who have an inadequate response to MTX therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00406419?term=STAGE+AND+RA&rank=15
Additional information can be found here:
http://www.researchra.com/
"SCRIPT: Ocrelizumab Compared to Placebo in
Patients With Active Rheumatoid Arthritis Who Don't Have a Response to
Anti-TNF-A Therapy"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Memphis, Jackson, Knoxville
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX) or leflunomide,
given either alone or in combination with other non-biologic DMARDs in
patients with active RA who have an inadequate response to anti-TNF-A
therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00476996?term=SCRIPT&rank=3
Additional information can be found here:
http://www.researchra.com/
"PRECISION : Prospective Randomized Evaluation of Celecoxib Integrated Safety vs. Ibuprofen Or Naproxen"
Type(s) of arthritis being studied: Rheumatoid, osteoarthritis
Status of study: RECRUITING
Study sites can be found in: Germantown, Bristol, Kingsport, Nashville, Jackson
Contact info: Pfizer CTgov Call Center, 1-800-718-1021
This study intends to study the risk of using celecoxib (i.e. Celebrex)
versus the use of NSAIDs for the treatment of arthritic pain. The focus
of risk will be on cardiovascular, gastrointestinal, and renal health.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00346216?order=2
"Safety and Effectiveness Study of
RWJ-445380 Cathepsin-S Inhibitor in Patients With Active Rheumatoid
Arthritis Despite Methotrexate Therapy"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Nashville
The purpose of this Phase II study is to evaluate the safety and
tolerability of 100, 200, and 300 mg/day doses of RWJ-445380 for up to
12 weeks in patients with active Rheumatoid Arthritis despite
methotrexate therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00425321?order=6
"Treatment of Arthritis With Syk Kinase Inhibition (TASKI-1)"
Type(s) of arthritis being studied: rheumatoid
Status of study: RECRUITING
Study sites can be found in: Jackson, Memphis
Contact info: Elliott Grossbard, M.D.; 650-624-1378, egrossbard@rigel.com
The goal of this study is to assess the preliminary efficacy of up to three different dosage regimens of R788.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00326339?order=7
"A Safety and Pharmacokinetics Study in Patients With Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Chattanooga
Contact info: 1-877-285-4559 or 1-317-615-4559
The purpose of this study is to examine the safety and tolerability of the LY2189102 antibody in rheumatoid arthritis patients.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00380744?order=15
Texas
"TASKi: Treatment of Arthritis With Syk Kinase Inhibition"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Austin and San Antonio
Contact info: http://www.taskistudy.com/Page.aspx?Page=Screen9
The TASKi study is composed of two studies.
(1)
A Phase II, Multicenter, Randomized, Double-Blind, Placebo-Controlled,
Parallel Dose Study of R935788 in Patients with Rheumatoid Arthritis
who have failed at least one biologic.
(2) A Phase II, Multicenter,
Randomized, Double-Blind, Placebo-Controlled, Parallel Dose Study of
Two Doses of R935788 in Rheumatoid Arthritis Patients Failing to
respond to Methotrexate.
Criteria for admittance and further information can be found here:
http://www.taskistudy.com/PreScreen.aspx
Additional information can be found here:
http://www.taskistudy.com
"FILM: The Safety and Efficacy of Ocrelizumab in Combination With Methotrexate in Patients With Active Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: San Antonio, El Paso, Lubbock, Dallas, Austin, Sugar Land, Ft. Worth, Amarillo, Houston
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX), compared with
methotrexate alone in patients with active RA of at least 3 months and
less than 5 years duration (and who are naive to MTX).
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00485589?term=FILM&rank=7
Additional information can be found here:
http://www.researchra.com/
"STAGE: Ocrelizumab Compared to Placebo in Patients With Active Rheumatoid Arthritis Continuing Methotrexate Treatment"
Type(s) of arthritis being studied: Rheumatoid
Status of study: NO LONGER ENROLLING
Study sites can be found in: San Antonio, Lubbock, Dallas, Houston, Waco, Austin, Amarillo, Mesquite
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX) in patients with
active RA who have an inadequate response to MTX therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00406419?term=STAGE+AND+RA&rank=15
Additional information can be found here:
http://www.researchra.com/
"SCRIPT: Ocrelizumab Compared to Placebo in
Patients With Active Rheumatoid Arthritis Who Don't Have a Response to
Anti-TNF-A Therapy"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Dallas, San Antonio, Austin, Lubbock, Sugar Land, Amarillo, Mesquite
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX) or leflunomide,
given either alone or in combination with other non-biologic DMARDs in
patients with active RA who have an inadequate response to anti-TNF-A
therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00476996?term=SCRIPT&rank=3
Additional information can be found here:
http://www.researchra.com/
"PRECISION : Prospective Randomized Evaluation of Celecoxib Integrated Safety vs. Ibuprofen Or Naproxen"
Type(s) of arthritis being studied: Rheumatoid, osteoarthritis
Status of study: RECRUITING
Study sites can be found in: Plano, San Antonio, Dallas, Fort Worth, Garland, Amarillo, Arlington, Bedford, Mesquite, McAllen
Contact info: Pfizer CTgov Call Center, 1-800-718-1021
This study intends to study the risk of using celecoxib (i.e. Celebrex)
versus the use of NSAIDs for the treatment of arthritic pain. The focus
of risk will be on cardiovascular, gastrointestinal, and renal health.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00346216?order=2
"Multiple Ascending Dose Study of BMS-582949 in Patients With Stable Rheumatoid Arthritis on the Methotrexate Background"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Dallas, San Antonio,
This study intends to study the safety of taking methotrexate with BMS-582949.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00162292?order=3
"Safety and Effectiveness Study of
RWJ-445380 Cathepsin-S Inhibitor in Patients With Active Rheumatoid
Arthritis Despite Methotrexate Therapy"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Austin
The purpose of this Phase II study is to evaluate the safety and
tolerability of 100, 200, and 300 mg/day doses of RWJ-445380 for up to
12 weeks in patients with active Rheumatoid Arthritis despite
methotrexate therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00425321?order=6
"Treatment of Arthritis With Syk Kinase Inhibition (TASKI-1)"
Type(s) of arthritis being studied: rheumatoid
Status of study: RECRUITING
Study sites can be found in: Austin, El Paso
Contact info: Elliott Grossbard, M.D.; 650-624-1378, egrossbard@rigel.com
The goal of this study is to assess the preliminary efficacy of up to three different dosage regimens of R788.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00326339?order=7
"Long-Term Effectiveness And Safety Of CP-690,550 For The Treatment Of Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Dallas
Contact info: Pfizer CTgov Call Center, 1-800-718-1021
The purpose of this study is to determine the long-term effectiveness
and safety of CP-690,550 for the treatment of rheumatoid arthritis.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00413699?order=12
Utah
"FILM: The Safety and Efficacy of Ocrelizumab in Combination With Methotrexate in Patients With Active Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Ogden
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX), compared with
methotrexate alone in patients with active RA of at least 3 months and
less than 5 years duration (and who are naive to MTX).
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00485589?term=FILM&rank=7
Additional information can be found here:
http://www.researchra.com/
"STAGE: Ocrelizumab Compared to Placebo in Patients With Active Rheumatoid Arthritis Continuing Methotrexate Treatment"
Type(s) of arthritis being studied: Rheumatoid
Status of study: NO LONGER ENROLLING
Study sites can be found in: Salt Lake City
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX) in patients with
active RA who have an inadequate response to MTX therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00406419?term=STAGE+AND+RA&rank=15
Additional information can be found here:
http://www.researchra.com/
"A Phase 2 Study to Evaluate the Efficacy and Safety of 60mg of MM-093 in Patients With Active Rheumatoid Arthritis"
Type(s) of arthritis being studied: rheumatoid
Status of study: RECRUITING
Study sites can be found in: Salt Lake City
Contact info: Jayne Belanger; 978-568-8880, jbelanger@clinquestinc.com
The purpose of this study is to determine whether MM-093 is safe and effective in the treatment of rheumatoid arthritis.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00458146?order=10
Vermont
Sorry, no trials available.
Virginia
"STAGE: Ocrelizumab Compared to Placebo in Patients With Active Rheumatoid Arthritis Continuing Methotrexate Treatment"
Type(s) of arthritis being studied: Rheumatoid
Status of study: NO LONGER ENROLLING
Study sites can be found in: Arlington
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX) in patients with
active RA who have an inadequate response to MTX therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00406419?term=STAGE+AND+RA&rank=15
Additional information can be found here:
http://www.researchra.com/
"SCRIPT: Ocrelizumab Compared to Placebo in
Patients With Active Rheumatoid Arthritis Who Don't Have a Response to
Anti-TNF-A Therapy"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Arlington, Norfolk
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX) or leflunomide,
given either alone or in combination with other non-biologic DMARDs in
patients with active RA who have an inadequate response to anti-TNF-A
therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00476996?term=SCRIPT&rank=3
Additional information can be found here:
http://www.researchra.com/
"PRECISION : Prospective Randomized Evaluation of Celecoxib Integrated Safety vs. Ibuprofen Or Naproxen"
Type(s) of arthritis being studied: Rheumatoid, osteoarthritis
Status of study: RECRUITING
Study sites can be found in: Daville, Roanoke, Newport News, Falls
Church, Chesapeake, Portsmouth, Petersburg, Norfolk, Williamsburg
Contact info: Pfizer CTgov Call Center, 1-800-718-1021
This study intends to study the risk of using celecoxib (i.e. Celebrex)
versus the use of NSAIDs for the treatment of arthritic pain. The focus
of risk will be on cardiovascular, gastrointestinal, and renal health.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00346216?order=2
"Treatment of Arthritis With Syk Kinase Inhibition (TASKI-1)"
Type(s) of arthritis being studied: rheumatoid
Status of study: RECRUITING
Study sites can be found in: Chesapeake
Contact info: Elliott Grossbard, M.D.; 650-624-1378, egrossbard@rigel.com
The goal of this study is to assess the preliminary efficacy of up to three different dosage regimens of R788.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00326339?order=7
Washington
"TASKi: Treatment of Arthritis With Syk Kinase Inhibition"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Spokane
Contact info: http://www.taskistudy.com/Page.aspx?Page=Screen9
The TASKi study is composed of two studies.
(1)
A Phase II, Multicenter, Randomized, Double-Blind, Placebo-Controlled,
Parallel Dose Study of R935788 in Patients with Rheumatoid Arthritis
who have failed at least one biologic.
(2) A Phase II, Multicenter,
Randomized, Double-Blind, Placebo-Controlled, Parallel Dose Study of
Two Doses of R935788 in Rheumatoid Arthritis Patients Failing to
respond to Methotrexate.
Criteria for admittance and further information can be found here:
http://www.taskistudy.com/PreScreen.aspx
Additional information can be found here:
http://www.taskistudy.com
"STAGE: Ocrelizumab Compared to Placebo in Patients With Active Rheumatoid Arthritis Continuing Methotrexate Treatment"
Type(s) of arthritis being studied: Rheumatoid
Status of study: NO LONGER ENROLLING
Study sites can be found in: Vancouver, Spokane, Yakima, Tacoma, Everett, Olympia
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX) in patients with
active RA who have an inadequate response to MTX therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00406419?term=STAGE+AND+RA&rank=15
Additional information can be found here:
http://www.researchra.com/
"SCRIPT: Ocrelizumab Compared to Placebo in
Patients With Active Rheumatoid Arthritis Who Don't Have a Response to
Anti-TNF-A Therapy"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Vancouver, Spokane, Yakima, Tacoma, Everett, Olympia, Seattle
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX) or leflunomide,
given either alone or in combination with other non-biologic DMARDs in
patients with active RA who have an inadequate response to anti-TNF-A
therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00476996?term=SCRIPT&rank=3
Additional information can be found here:
http://www.researchra.com/
"PRECISION : Prospective Randomized Evaluation of Celecoxib Integrated Safety vs. Ibuprofen Or Naproxen"
Type(s) of arthritis being studied: Rheumatoid, osteoarthritis
Status of study: RECRUITING
Study sites can be found in: Wenatchee, Tacoma, Spokane, Yakima,
Contact info: Pfizer CTgov Call Center, 1-800-718-1021
This study intends to study the risk of using celecoxib (i.e. Celebrex)
versus the use of NSAIDs for the treatment of arthritic pain. The focus
of risk will be on cardiovascular, gastrointestinal, and renal health.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00346216?order=2
"Efficacy, Safety and Tolerability of ACZ885 in Patients With Active Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Tacoma
Contact info: Novartis Pharmaceuticals New Jersey, United States, 1-862-778-8300
This Phase II study intends to collect long-term safety and
tolerability data with 300 mg of experimental drug ACZ885 in patients
with active rheumatoid arthritis (RA).
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00471198?order=2
"Efficacy, Safety and Tolerability of ACZ885 in Patients With Active Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Tacoma
The purpose of this study is to evaluate risk-benefit of three
subcutaneous dose regimens of ACZ885, added on to stable methotrexate
therapy, compared to placebo in patients with active rheumatoid
arthritis.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00424346?order=7
"Long-Term Effectiveness And Safety Of CP-690,550 For The Treatment Of Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Tacoma
Contact info: Pfizer CTgov Call Center, 1-800-718-1021
The purpose of this study is to determine the long-term effectiveness
and safety of CP-690,550 for the treatment of rheumatoid arthritis.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00413699?order=12
West Virginia
"PRECISION : Prospective Randomized Evaluation of Celecoxib Integrated Safety vs. Ibuprofen Or Naproxen"
Type(s) of arthritis being studied: Rheumatoid, osteoarthritis
Status of study: RECRUITING
Study sites can be found in: Beckley, Parkers, Lewisburg
Contact info: Pfizer CTgov Call Center, 1-800-718-1021
This study intends to study the risk of using celecoxib (i.e. Celebrex)
versus the use of NSAIDs for the treatment of arthritic pain. The focus
of risk will be on cardiovascular, gastrointestinal, and renal health.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00346216?order=2
Wisconsin
"FILM: The Safety and Efficacy of Ocrelizumab in Combination With Methotrexate in Patients With Active Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Onalaska
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX), compared with
methotrexate alone in patients with active RA of at least 3 months and
less than 5 years duration (and who are naive to MTX).
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00485589?term=FILM&rank=7
Additional information can be found here:
http://www.researchra.com/
"STAGE: Ocrelizumab Compared to Placebo in Patients With Active Rheumatoid Arthritis Continuing Methotrexate Treatment"
Type(s) of arthritis being studied: Rheumatoid
Status of study: NO LONGER ENROLLING
Study sites can be found in: Onalaska, Glendale
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX) in patients with
active RA who have an inadequate response to MTX therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00406419?term=STAGE+AND+RA&rank=15
Additional information can be found here:
http://www.researchra.com/
"SCRIPT: Ocrelizumab Compared to Placebo in
Patients With Active Rheumatoid Arthritis Who Don't Have a Response to
Anti-TNF-A Therapy"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Onalaska, Glendale
Contact info: Genentech Study Prescreening Number, 1-877-STUDY16
This is a randomized, placebo-controlled, double-blind, multicenter,
parallel-group phase III study to investigate the efficacy and safety
of ocrelizumab in combination with methotrexate (MTX) or leflunomide,
given either alone or in combination with other non-biologic DMARDs in
patients with active RA who have an inadequate response to anti-TNF-A
therapy.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct2/show/NCT00476996?term=SCRIPT&rank=3
Additional information can be found here:
http://www.researchra.com/
"PRECISION : Prospective Randomized Evaluation of Celecoxib Integrated Safety vs. Ibuprofen Or Naproxen"
Type(s) of arthritis being studied: Rheumatoid, osteoarthritis
Status of study: RECRUITING
Study sites can be found in: Madison, Wauwatosa, Wausau
Contact info: Pfizer CTgov Call Center, 1-800-718-1021
This study intends to study the risk of using celecoxib (i.e. Celebrex)
versus the use of NSAIDs for the treatment of arthritic pain. The focus
of risk will be on cardiovascular, gastrointestinal, and renal health.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00346216?order=2
"Long-Term Effectiveness And Safety Of CP-690,550 For The Treatment Of Rheumatoid Arthritis"
Type(s) of arthritis being studied: Rheumatoid
Status of study: RECRUITING
Study sites can be found in: Onalaska
Contact info: Pfizer CTgov Call Center, 1-800-718-1021
The purpose of this study is to determine the long-term effectiveness
and safety of CP-690,550 for the treatment of rheumatoid arthritis.
Criteria for admittance and further information can be found here:
http://clinicaltrials.gov/ct/show/NCT00413699?order=12
Wyoming
Sorry, no trials available.
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